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Substrate-targeting gamma-secretase modulators

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Substrate-targeting gamma-secretase modulators

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Semisynthesis and Enzymatic Preparation of Post-translationally Modified α-Synuclein

The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain

Real-time Protein Aggregation Monitoring based on a Simultaneous Light Scattering Investigation and a Bloch Surface Wave-based Approach

Identification of new Presenilin-1 phosphosites: implication for gamma-secretase activity and A beta production

The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-beta peptides

Real-time Protein Aggregation Monitoring with a Bloch Surface Wavebased Approach

The Role of γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of γ-Secretase Activity and Amyloid-β Generation

Real-time Amyloid Aggregation Monitoring with a Photonic Crystal-based Approach

Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production

Chemical strategies for controlling protein folding and elucidating the molecular mechanisms of amyloid formation and toxicity