pH prediction and control in bioprocesses using mid-infrared spectroscopy
Graph Chatbot
Chat with Graph Search
Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.
DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.
A tripodal ligand based on the 8-hydroxyquinolinate binding unit yields a soluble and highly stable bis-hydrated Gd3+ complex in water (pGd = 19.2(3)) with relaxivity change in the pH range 4.5-7.4 and Nd3+, Yb3+ analogues with sizeable NIR emission upon e ...
This Ph.D. work deals with the development of lanthanide-based bioprobes for biomedical analyses and imaging. For this purpose, two different approaches have been followed, one focusing on visible-emitting complexes, while the second addresses the sensitiz ...
Kinetic hard-modelling is often the method of choice in order to determine kinetic parameters of reactions by non-linear optimisation and fitting of measured data. In spectroscopy, kinetic hard-modelling allows decomposing time and wavelength resolved data ...
Group contribution methods for the calculation of an activity coefficient such as UNIFAC (universal factorial activity coefficient) currently do not take into account sterical effects. Consequently one of the major deficiencies of such methods is their ina ...
In recent years, chemometric methods for the analysis of multivariate kinetic data have considerably progressed. Kinetic hard-modelling is one of these methods that is based on the rate law and used to determine the kinetic parameters (e.g. rate constants) ...
This thesis aimed at developing new, simple methods of calibration for on-line monitoring of bioprocesses by Fourier-transform mid-infrared spectroscopy (FTIR). The conventional calibration approach implies the preparation and measurement of a large number ...
The oxidation of iodide by synthetic birnessite (delta-MnO2) was studied in perchlorate media in the pH range 4-8. Iodine (I-2) was detected as an oxidation product that was subsequently further oxidized to iodate (IO3-). The third order rate constants, se ...
We review fundamental and applied acid-base equilibrium chemistry useful to microfluidic electrokinetics. We present elements of acid-base equilibrium reactions and derive rules for pH calculation for simple buffers. We also present a general formulation t ...
A novel method is presented for the rigorous propagation of uncertainties in initial concentrations and in dosing rates into the errors in the rate constants fitted by multivariate kinetic hard-modelling of spectroscopic data using the Newton–Gauss–Levenbe ...
A single spectra library was used to monitor on-line, by mid-infrared spectroscopy, nine different batch cultures of Escherichia coli performed with various medium compositions, including chemically complex formulations. Whereas the classic chemometrics ap ...