Palladium-catalyzed three-component synthesis of 3-(diarylmethylene)oxindoles through a domino Sonogashira/carbopalladation/C-H activation/C-C bond-forming sequence
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Transition-metal catalyzed C-H functionalizations have impacted and changed synthetic approaches towards the construction of relevant complex molecules, comprising natural products, active pharmaceutical ingredients, and organic materials. This thesis desc ...
Recent advances in transition metal catalyzed C-H activation are revolutionizing synthetic organic chemistry, and application of this powerful synthetic tool in the context of total synthesis of complex natural products is beginning to blossom. This thesis ...
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Two main topics were addressed in this manuscript: (1) New methods for indoles and [3,4]-fused oxindoles syntheses; (2) Copper-catalyzed/mediated difunctionalization of alkenes with alkylnitriles. Given the omnipresent character of the indole and oxindole ...
Supramolecular rubbers incorporating a large number of physical cross-links through cooperative hydrogen bonds display high self-healing properties but limited solvent and creep resistance due to the lack of chemical cross-links. Increasing both chemical c ...
The bond properties between concrete and steel reinforcement influence structural stiffness and deformation behavior as a result of tension stiffening. In specific cases, the load-bearing capacity of engineering structures depends on the deformation behavi ...
An efficient method for the synthesis of amides via Pd-catalyzed oxidative carbonylation of C(sp(3))-H bonds with CO and amines is described. The route efficiently provides substituted phenyl amides from alkanes. ...
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Norrish-type-II reaction on a semiquinone radical: Stable semiquinone radicals serve as novel molecular platforms on which a Norrish-type-II photoreaction can be initiated. A detailed reaction scheme involving a 1,5-hydrogen transfer followed by a cyclizat ...
