Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
Publication
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
The limited availability of bioactive natural products for pharmaceutical studies and drug development is a problem that can be solved, in principle, by total synthesis. The potent antitumor marine natural products ecteinascidin 597 (I; R = Me) and ecteinascidin 583 (I; R = H) have now been synthesized from readily accessible starting materials in a highly convergent and stereoselective fashion (see scheme). [on SciFinder (R)]
Christian Heinis, Xinjian Ji, Alexander Lund Nielsen