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An efficient synthesis of 2-imino-4-thiazolidinones from readily accessible alkyl or aryl trichloromethylcarbinols with thioureas, under mild conditions, is reported. A one-pot three-component synthesis of the title compds. from aldehyde, chloroform and thiourea was also developed. [on SciFinder (R)]
Qian Wang, Jieping Zhu, Takuji Fujii, Simone Gallarati
Giovanni De Micheli, Luca Gaetano Amarù, Eleonora Testa
Giovanni De Micheli, Mathias Soeken, Winston Jason Haaswijk