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The Microbe browser for comparative genomics

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KRAB zinc-finger proteins and their transposable element targets: between antagonism and cooperation

Jonas Caspar De Tribolet-Hardy

There are 377 Krüppel-associated box (KRAB) domain-containing zinc finger proteins (KZFPs) in the human genome, making them the largest family of transcription factors. KZFPs are defined by a N-terminal KRAB domain and several zinc-finger domains arranged ...

EPFL2022

BACKGROUND. Clinical Decision Support Systems (CDSS) are point-of-care questionnaires that guide consultations to evidence-based predictions with the aim of standardizing care and optimizing resource allocation. The data collected in these tools contain po ...

2022

OPTIMADE, an API for exchanging materials data

Nicola Marzari, Giovanni Pizzi, Martin Uhrin, Boris Kozinsky, Christoph Leopold Talirz, Andrius Merkys, Snehal Pramod Kumbhar, Casper Welzel Andersen, Gian-Marco Rignanese, Matthias Scheffler

The Open Databases Integration for Materials Design (OPTIMADE) consortium has designed a universal application programming interface (API) to make materials databases accessible and interoperable. We outline the first stable release of the specification, v ...

NATURE PORTFOLIO2021

Rapid identification and interpretation of gene‐environment associations using the new R.SamBada landscape genomics pipeline

Stéphane Joost, Oliver Michele Selmoni, Estelle Rochat, Sylvie Stucki, Kevin Leempoel, Elia Vajana

Samβada is a genome‐environment association (GEA) software, designed to search for signatures of local adaptation. However, pre‐ and post‐processing of data can be labour‐intensive, preventing wider uptake of the method. We have now developed R.SamBada, an ...

2019

This chapter aims to provide an overview of the fatigue life modeling and prediction methods for composite materials and structures, recalling methods used in the past, discovering the present status, and attempting to foresee future trends. ...

Elsevier2019

The impressive technological advances in genomic analysis and the significant drop in the cost of genome sequencing are paving the way to a variety of revolutionary applications in modern healthcare. In particular, the increasing understanding of the human ...

EPFL2018

We study user interaction with touchscreens based on swipe gestures for personal authentication. This approach has been analyzed only recently in the last few years in a series of disconnected and limited works. We summarize those recent efforts and then c ...

2018

Caching and Distributed Storage

Saeid Sahraei

A simple task of storing a database or transferring it to a different point via a communication channel turns far more complex as the size of the database grows large. Limited bandwidth available for transmission plays a central role in this predicament. I ...

EPFL2018

Modern industrial, government, and academic organizations are collecting massive amounts of data at an unprecedented scale and pace. The ability to perform timely, predictable and cost-effective analytical processing of such large data sets in order to ext ...

EPFL2016

The detection of cytosolic DNA by the sensor cGAS triggers potent antiviral responses. New data now propose that cGAS is regulated on a post-translational level by glutamylation. ...

Nature Publishing Group2016