DNA origami nanostructures for controlled therapeutic drug delivery

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Waveguide modes spatially resolved by low-loss STEM-EELS

In an era of new developments in nanomaterials analysis enabled by the unprecedented spatial and energy resolutions of electron energy-loss spectroscopy in the scanning transmission electron microscope (STEM-EELS), it remains that the vast majority of work ...

2021

Viscoelastic surface electrode arrays to interface with viscoelastic tissues

Stéphanie Lacour, Alix Esther Anne Trouillet, Nicolas Vachicouras, Florian Dylan Fallegger, Christina Myra Tringides

Bioelectronic interfacing with living tissues should match the biomechanical properties of biological materials to reduce damage to the tissues. Here, the authors present a fully viscoelastic microelectrode array composed of an alginate matrix and carbon-b ...

Nature Research2021

Nanophotonic biosensors harnessing van der Waals materials

Hatice Altug

Low-dimensional van der Waals (vdW) materials can harness tightly confined polaritonic waves to deliver unique advantages for nanophotonic biosensing. The reduced dimensionality of vdW materials, as in the case of two-dimensional graphene, can greatly enha ...

Nature Research2021

Fabrication and applications of AuAg alloy metasurfaces and hybrid metal dielectric nanoantennas

Debdatta Ray

The most prevalent materials used in the field of plasmonics are Au and Ag. However, for the past few years, the plasmonic community has also been looking for alternative materials that have lower losses than Au and higher stability than Ag. This thesis is ...

EPFL2021

Fabrication of micrometer-sized drops as templates for particles

Mathias Steinacher

Drops are omnipresent in our daily life for example in the form of rain drops or as oil drops in a salad dressing. On a technological basis, drops can be used to conduct chemical or biological reactions. These drops often serve as templates to produce mate ...

EPFL2021

Wireless soft microscale actuators and robotic devices to study mechanobiology

Raquel Filipa Penacho Parreira

Tissues morphogenesis and homeostasis involve the spatiotemporal regulation of mechanics at multiple scales. Characterization of mechanical properties of biological systems as well as investigating the effects of mechanical forces on biological function ar ...

EPFL2021

Systematic investigations of uranium carbide composites oxidation from micro- to nano-scale: Application to waste disposal

Nhât-Tân Vuong

The production of radioisotope beams at the ISOLDE (Isotope Separator OnLine DEvice) facility at CERN is achieved by irradiating target materials (e.g. uranium carbides and metal foils) with protons. The materials are usually operated at temperatures above ...

EPFL2021

Laser-induced liquid micro-jets for drug delivery

Jan Krizek

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Such contact-less devices provide several advantages such as better dose control, lateral and depth localisation, lower collateral damage than ...

EPFL2021

Transport and programmed release of nanoscale cargo from cells by using NETosis

Ardemis Anoush Boghossian, Alessandra Antonucci, Alice Judith Gillen, Daniel Meyer

Cells can take up nanoscale materials, which has important implications for understanding cellular functions, biocompatibility as well as biomedical applications. Controlled uptake, transport and triggered release of nanoscale cargo is one of the great cha ...

ROYAL SOC CHEMISTRY2020

A Drug Release Mechanism Controlled by Hydrophobic/Hydrophilic Balance of the Matrix. Theoretical and Experimental Perspectives

Maria-Alexandra Paun

Controlled drug release is a promising pathway of biomedicine, meant to suppress side effects with the aim of increasing patient's comfort. A route to achieve this goal represents the encapsulation of drugs into matrixes, capable to develop physical forces ...

REVISTA CHIMIE SRL2020

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Systematic investigations of uranium carbide composites oxidation from micro- to nano-scale: Application to waste disposal

Nhât-Tân Vuong

EPFL2021

A Drug Release Mechanism Controlled by Hydrophobic/Hydrophilic Balance of the Matrix. Theoretical and Experimental Perspectives

Maria-Alexandra Paun

REVISTA CHIMIE SRL2020