Publication

Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model

Related publications (32)

Cellular hallmarks reveal restricted aerobic metabolism at thermal limits

Pierre Gönczy, Coralie Busso, Aitana Neves da Silva

All organisms live within a given thermal range, but little is known about the mechanisms setting the limits of this range. We uncovered cellular features exhibiting signature changes at thermal limits in Caenorhabditis elegans embryos. These included chan ...

eLife Sciences Organisation2015

The chicken chorioallantoic membrane model in biology, medicine and bioengineering

Patrycja Nowak-Sliwinska

The chicken chorioallantoic membrane (CAM) is a simple, highly vascularized extraembryonic membrane, which performs multiple functions during embryonic development, including but not restricted to gas exchange. Over the last two decades, interest in the CA ...

Springer2014

The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A(165)

Jeffrey Alan Hubbell, Melody Swartz, Mikaël Martino

Synergy in the downstream signaling pathways of the vascular endothelial growth factor receptor-2 (VEGFR-2) and the integrin alpha v beta 3 is critical for blood vessel formation. Thus, agents that activate both receptors could possess efficient pro-angiog ...

Elsevier2013

Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion

Hubert van den Bergh, Patrycja Nowak-Sliwinska, Blaise Lovisa

Targeted angiostatic therapy receives major attention for the treatment of cancer and exudative age-related macular degeneration (AMD). Photodynamic therapy (PDT) has been used as an effective clinical approach for these diseases. Since PDT can cause an an ...

2012

An in vivo neovascularization assay for screening regulators of angiogenesis and assessing their effects on pre-existing vessels

Witold Waldemar Kilarski, Marcin Stefan Zielinski

Therapeutic regulation of tissue vascularization has appeared as an attractive approach to treat a number of human diseases. In vivo neovascularization assays that reflect physiological and pathological formation of neovessels are important in this effort. ...

Springer Netherlands2012

Effects of Photodynamic Therapy in Combination with Anti-Angiogenic Drugs on the Chicken Chorioallantoic Membrane Model

Photodynamic therapy (PDT) is clinically-approved in the treatment of angiogenic disorders, particularly eye diseases such as age-related macular degeneration (AMD) and skin cancers, such as basal cell carcinoma. PDT causes vascular occlusion resulting in ...

2011

Extracellular matrix in angiogenesis: dynamic structures with translational potential

Jeffrey Alan Hubbell

The vascular network is an integral component of most organs. Beyond assuring an adequate supply of oxygen and nutrients for normal tissue function, vascular structures provide also a critical interface in the balance of tissue homoeostasis and immune func ...

2011

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

Douglas Hanahan

Endothelial cells (ECs) in blood vessels under formation are stabilized by the recruitment of pericytes, both in normal tissues and during angiogenesis in pathologic situations, including neoplasia. In the tumor vasculature, besides supporting the function ...

2011

In vitro lymphatic endothelial morphogenesis

Carolyn Yong Pullin

Cell organization into functional multicellular three-dimensional structures is a long-standing challenge. In particular, engineering of vascularized tissues requires both blood and lymphatic neovascular network formation in a simultaneous and coordinated ...

EPFL2011

Vascular regrowth following photodynamic therapy in the chicken embryo chorioallantoic membrane

Hubert van den Bergh, Patrycja Nowak-Sliwinska

Photodynamic therapy (PDT) induces damage to the endothelium, which can lead to increased vascular permeability and, under intensive PDT conditions, even to platelet aggregation, vasoconstriction, and blood flow stasis. Eventually, ischemia, hypoxia, and i ...

Springer Netherlands2010

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.