Microfluidic Chips for Point-of-Care Immunodiagnostics
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A microfluidic platform for a heterogeneous competitive immunoassay of human immunoglobulin G (IgG) employing Cy5-human IgG as tracer and Cy3-mouse IgG as internal standard was developed. The device consisted of microchannels made of poly(dimethylsiloxane) ...
We introduce powder blasting using a pressurised nozzle and a metallic mask as a new promising technology for microsystem fabrication. We study basic parameters of this powder blasting erosion process as well as mask-geometry effects on the erosion rate. W ...
This review gives an overview of developments in the field of microchip analysis for clinical diagnostic and forensic applications. The approach chosen to review the literature is different from that in most microchip reviews to date, in that the informati ...
We have designed and realised a new type of microsystem for the electrical characterisation of epithelial cell layers for biomedical diagnostic purposes. We have used deep plasma and other micromachining procedures for the fabrication of vias and microflui ...
Poly(dimethylsiloxane) (PDMS) appeared recently as a material of choice for rapid and accurate replication of polymer-based microfluidic networks. However, due to its hydrophobicity, the surface strongly interacts with apolar analytes or species containing ...
This paper describes the development of polyimide-based microfluidic devices. A layer transfer and lamination technique is used to fabricate flexible microfluidic channels in various shapes and with a wide range of dimensions. High bond strengths can be ac ...
A set of new technologies to fabricate microchannels using photosensitive polymer materials is presented. They are based on the use of polymers, hereafter called photopolymers, that are cured with UV light under a mask exposure. The basic material is ail e ...