A novel one-step microfabrication process of SU-8 films for the development of inexpensive light-weight and small size optical glucose micro-biosensors is proposed. Experimental work was carried out in order to investigate whether SU-8 photoresists, which are polymers widely used in MEMS applications, can be utilised as immobilisation matrices for the simultaneous encapsulation of glucose oxidase and an oxygen-sensitive fluorescent indicator. The immobilisation of the enzyme, the encapsulation of the indicator and the patterning of the custom-made SU-8 take place simultaneously, thus simplifying the microfabrication process.
Martinus Gijs, Hüseyin Baris Atakan, Rongrong Xiang
Luis Guillermo Villanueva Torrijo, Annalisa De Pastina, Tom Larsen, Andrea Lozzi, Kaitlin Marie Howell, Muhammad Faizan