Sequence alignmentIn bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix. Gaps are inserted between the residues so that identical or similar characters are aligned in successive columns.
Diophantine approximationIn number theory, the study of Diophantine approximation deals with the approximation of real numbers by rational numbers. It is named after Diophantus of Alexandria. The first problem was to know how well a real number can be approximated by rational numbers. For this problem, a rational number a/b is a "good" approximation of a real number α if the absolute value of the difference between a/b and α may not decrease if a/b is replaced by another rational number with a smaller denominator.
Analog-to-digital converterIn electronics, an analog-to-digital converter (ADC, A/D, or A-to-D) is a system that converts an analog signal, such as a sound picked up by a microphone or light entering a digital camera, into a digital signal. An ADC may also provide an isolated measurement such as an electronic device that converts an analog input voltage or current to a digital number representing the magnitude of the voltage or current. Typically the digital output is a two's complement binary number that is proportional to the input, but there are other possibilities.
White noiseIn signal processing, white noise is a random signal having equal intensity at different frequencies, giving it a constant power spectral density. The term is used, with this or similar meanings, in many scientific and technical disciplines, including physics, acoustical engineering, telecommunications, and statistical forecasting. White noise refers to a statistical model for signals and signal sources, rather than to any specific signal.
Sequence analysisIn bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand its features, function, structure, or evolution. Methodologies used include sequence alignment, searches against biological databases, and others. Since the development of methods of high-throughput production of gene and protein sequences, the rate of addition of new sequences to the databases increased very rapidly.
Remote controlIn electronics, a remote control (also known as a remote or clicker) is an electronic device used to operate another device from a distance, usually wirelessly. In consumer electronics, a remote control can be used to operate devices such as a television set, DVD player or other home appliance. A remote control can allow operation of devices that are out of convenient reach for direct operation of controls. They function best when used from a short distance. This is primarily a convenience feature for the user.
Posterior probabilityThe posterior probability is a type of conditional probability that results from updating the prior probability with information summarized by the likelihood via an application of Bayes' rule. From an epistemological perspective, the posterior probability contains everything there is to know about an uncertain proposition (such as a scientific hypothesis, or parameter values), given prior knowledge and a mathematical model describing the observations available at a particular time.
Open-source software developmentOpen-source software development (OSSD) is the process by which open-source software, or similar software whose source code is publicly available, is developed by an open-source software project. These are software products available with its source code under an open-source license to study, change, and improve its design. Examples of some popular open-source software products are Mozilla Firefox, Google Chromium, Android, LibreOffice and the VLC media player. In 1997, Eric S. Raymond wrote The Cathedral and the Bazaar.
Dirichlet's approximation theoremIn number theory, Dirichlet's theorem on Diophantine approximation, also called Dirichlet's approximation theorem, states that for any real numbers and , with , there exist integers and such that and Here represents the integer part of . This is a fundamental result in Diophantine approximation, showing that any real number has a sequence of good rational approximations: in fact an immediate consequence is that for a given irrational α, the inequality is satisfied by infinitely many integers p and q.
Business models for open-source softwareCompanies whose business centers on the development of open-source software employ a variety of business models to solve the challenge of how to make money providing software that is by definition licensed free of charge. Each of these business strategies rests on the premise that users of open-source technologies are willing to purchase additional software features under proprietary licenses, or purchase other services or elements of value that complement the open-source software that is core to the business.
