Genetic Association of Recovery from Eating Disorders: The Role of GABA Receptor SNPs
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Background: Mood disorders are polygenic disorders in which the alteration of several susceptibility genes results in dysfunctional mood regulation. However, the molecular mechanisms underlying their transcriptional dysregulation are still unclear. The tra ...
"We conducted an evaluative research on a sample of participants to a Geneva program aiming to increase the access of young people to culture. Once this research was done, we developed questions concerning how identity develops among these people. The mode ...
Several psychobiological factors are associated with vulnerability/resilience to stress-induced depression. Emerging evidence indicates behavioral traits, such as anxiety, can be related to depression-like symptoms after exposure to chronic stress. However ...
Objective: Although low weight is a key factor contributing to the high mortality in anorexia nervosa (AN), it is unclear how AN patients sustain low weight compared with bulimia nervosa (BN) patients with similar psychopathology. Studies of genes involved ...
When many hypotheses are tested simultaneously, the control of the number of false rejections is often the principal consideration. In practice, this is insatisfacory since we also have to keep in mind the power of detecting true effects. At the moment, th ...
Affective symptoms such as anxiety and depression are frequently observed in patients with epilepsy. The mechanisms of comorbidity of epilepsy and affective disorders, however, remain unclear. Diverse models are traditionally used in epilepsy research, inc ...
We performed association studies with 5,151 SNPs that were judged as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN) based on location under reported linkage peaks, previous results in the literature (182 candidate ge ...
Significance testing is a crucial step in metabolic biomarker recovery from the metabolome-wide latent variables computed by multivariate statistical analysis. In this study we propose an algorithm based on the landscape of the covariance/correlation ratio ...
This paper describes a new kind of genetic representation called analog genetic encoding (AGE). The representation is aimed at the evolutionary synthesis and reverse engineering of circuits and networks such as analog electronic circuits, neural networks, ...
This analysis is a follow-up to an earlier investigation of 182 genes selected as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN). As those initial case-control results revealed no statistically significant difference ...