Quantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy
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Gold nanoparticles are widely used in various applications in fields including chemistry, engineering, biology, medicine, and electronics. These materials can be synthesized and modified with ligands containing different functional groups. Among nanopartic ...
Optical Coherence Microscopy (OCM) is a three-dimensional imaging technique that provides cross-sectional views of the subsurface microstructure of biological tissue, with a high axial and lateral resolution. In OCM, a low time coherence light source is sp ...
EPFL2012
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In this paper, we present an automated approach to quantify information about three-dimensional (3D) morphology, hemoglobin content and density of mature red blood cells (RBCs) using off-axis digital holographic microscopy (DHM) and statistical algorithms. ...
Optical Society of America2012
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We consider a blind calibration problem in a compressed sensing measurement system in which each sensor introduces an unknown phase shift to be determined. We show that this problem can be approached similarly to the problem of phase retrieval from quadrat ...
2013
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X-ray differential phase-contrast tomography is a recently-developed modality for the imaging of low-contrast biological samples. Its mathematical model is based on the first derivative of the Radon transform and the images, in practice, are reconstructed ...
The fabrication of oxide-dispersion-strengthened (ODS) steels is a multi-stage process involving powder ball milling, degassing and consolidation by hot isostatic pressing. Y is introduced by mechanical alloying (MA) with either Y2O3 or Fe2Y so a high dens ...
It is accepted that the ligand shell morphology of nanoparticles coated with a monolayer of molecules can be partly responsible for important properties such as cell membrane penetration and wetting. When binary mixtures of molecules coat a nanoparticle, t ...
Accurate extraction of cell outlines from microscopy images is essential for analysing the dynamics of migrating cells. Phase-contrast microscopy is one of the most common and convenient imaging modalities for observing cell motility because it does not re ...
Our contribution in this paper is two fold. First, we propose a novel discretization of the forward model for differential phase-contrast imaging that uses B-spline basis functions. The approach yields a fast and accurate algorithm for implementing the for ...
Stimulated Emission Depletion (STED) microscopy enables subdiffraction resolution in the imaging plane. However, STED's lateral improvement in resolution is generally better than the enhancement in the axial direction. Here, we combine conventional STED su ...