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Biothermodynamics of live cells: a tool for biotechnology and biochemical engineering

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Dissipation as variable in cartilage mechanobiology

Philippe Abdel Sayed

Mechanobiology is the analysis of the role of mechanical forces in educing a molecular response in cells. Nowadays, mechanobiology may contribute to clinical progress. In particular, mechanical stimulation has been proposed to induce chondrogenesis in engi ...

EPFL2013

Fluid-structure thermal coupling and ablation effects in atmospheric entry

Ojas Joshi

This thesis deals with the modelling of fundamental aspects of the mission engineering, the physics, and the constraints of atmospheric entry of space vehicles. The aim of this work is to formulate a coupled approach for the modelling and the simulation of ...

EPFL2013

Data, Parameters & Nonlinearities: Development and Applications of Large-scale Dynamic Models of Metabolism

Vassily Hatzimanikatis, Ljubisa Miskovic, Keng Cher Soh, Anirikh Chakrabarti

Dynamic nonlinear models of metabolism offer a significant advantage as compared to constraint-based stoichiometric descriptions. However, progress in the development of large-scale nonlinear models has been hindered by both structural and quantitative unc ...

2013

Towards the Glass Transition in Vibrated Granular Matter

Alessandro Luigi Sellerio

Granular materials are large sets of macroscopic particles that interact solely via contact forces. The static behavior depends on the contact network and on the surface friction forces between grains; when they are set in motion (typically by vibrations) ...

EPFL2012

Temperature effect on connective tissue cells

Philippe Abdel Sayed, Salim Elias Darwiche

Intervertebral discs (IVD) are soft tissues that have viscoelastic behavior. Under cyclic loading, viscoelastic tissues dissipate the mechanical loading through the production of heat. In IVD, it is hypothesized that heat cannot be convected from the nucle ...

2012

Maximum entropy production, carbon assimilation, and the spatial organization of vegetation in river basins

Andrea Rinaldo

The spatial organization of functional vegetation types in river basins is a major determinant of their runoff production, biodiversity, and ecosystem services. The optimization of different objective functions has been suggested to control the adaptive be ...

Natl Acad Sciences2012

Lab on a chip technologies for algae detection: a review

Yves Bellouard

Over the last few decades, lab on a chip technologies have emerged as powerful tools for high-accuracy diagnosis with minute quantities of liquid and as tools for exploring cell properties in general. In this paper, we present a review of the current statu ...

2012

ECOS 2010 Volume I (Thermodynamics)

ECOS2010 - 23rd International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems, June 14-17 2010, Lausanne, Switzerland Ecoefficiency and renewable energy for a sustainable world + Developments, application ...

CreateSpace2011

Hydrodynamics and the Fluctuation Theorem

Giuseppe Foffi, Maxim Belushkin

The fluctuation theorem is a pivotal result of statistical physics. It quantifies the probability of observing fluctuations which are in violation of the second law of thermodynamics. More specifically, it quantifies the ratio of the probabilities of obser ...

2011

Thermomechanical Hysteresis of Biological and Synthetic Hydrogels

Arne Christian Vogel

The nucleus pulposus of the intervertebral disc is a gelatinous viscous hydrogel that has an essential role in the mechanics of the intervertebral disc joint. The viscoelastic properties of the nucleus pulposus significantly change in the course of time an ...

EPFL2011