Publication

Spinal Subarachnoid Space Pressure Measurements in an In Vitro Spinal Stenosis Model: Implications on Syringomyelia Theories

Related publications (45)

Ventricle Equilibrium Position in Healthy and Normal Pressure Hydrocephalus Brains Using an Analytical Model

Jean-Marie Drezet, Bryn Andrew Martin, Kamal Shahim

The driving force that causes enlargement of the ventricles remains unclear in case of normal pressure hydrocephalus (NPH). Both healthy and NPH brain conditions are characterized by a low transparenchymal pressure drop, typically 1 mm Hg. The present pape ...

2012

Bio Simulation of Brain Ventricle Dilation in Normal Pressure Hydrocephalus

Kamal Shahim

Hydrocephalus is a brain disease wherein the ventricles dilate and compress the parenchyma towards the skull. It is primarily characterized by the disruption of the cerebrospinal fluid (CSF) flow within the ventricular system. Normal pressure hydrocephalus ...

EPFL2011

Calculation of intracranial pressure in human brain using Darcy's and Biot's models

Jean-Marie Drezet, Kamal Shahim

Cerebrospinal fluid (CSF) is a colourless liquid that fills the ventricular space and serves several functions like buoyancy, chemical stability and protection. CSF is produced within the ventricles and partly by the ependyma cells. Part of it seeps toward ...

Taylor & Francis2011

Cerebrospinal fluid hydrodynamics in type I Chiari malformation

Bryn Andrew Martin

Purpose: The objective of this study was to review past studies that have used engineering analysis to examine cerebrospinal fluid hydrodynamics in cranial and spinal subarachnoid spaces in both healthy humans and those affected by type I Chiari malformati ...

2011

Finite element analysis of normal pressure hydrocephalus: influence of CSF content and anisotropy in permeability

Jean-François Molinari, Jean-Marie Drezet, Kamal Shahim

Hydrocephalus is a cerebral disease where brain ventricles enlarge and compress the brain parenchyma towards the skull leading to symptoms like dementia, walking disorder and incontinence. The origin of normal pressure hydrocephalus is still obscure. In or ...

Taylor & Francis2010

Geometry- and load-specific optimization of the collagen network's fibre orientation in the lumbar spine's annulus fibrosus

Andreas Schmocker

In Europe, low back pain (LBP) affects the quality of life of up to 30% of the active population. Although the origin of LBP is not well identified and is probably not unique, epidemiological studies suggest that the severity of the disease is correlated w ...

2010

Virtual reality simulator for the training of lumbar punctures

Friedhelm Christoph Hummel

Lumbar puncture (LP) is performed by inserting a needle into the spinal canal to extract cerebrospinal fluid for diagnostic purposes. A virtual reality (VR) lumbar puncture simulator based on real patient data has been developed and evaluated. ...

Schattauer2009

Fluid mechanics of intrathecal drug delivery

Radboud Michael Nelissen

The aim of this principally experimental study is to understand from fluid mechanic principles why an insignificant anesthetic dose administered as a short bolus into the cerebrospinal fluid inside the subarachnoid space provides greater pain relief than a ...

EPFL2008

Optimization of the treatment of hydrocephalus by the non-invasive measurement of the intra-cranial pressure

Alec Ginggen

This thesis work aims to optimize the treatment of hydrocephalus. It consists of two distinct objectives: the optimization of the diagnosis of patients implanted with a shunt system for the derivation of cerebro-spinal fluid (CSF) and the optimization of t ...

EPFL2007

Analysis of the stability of a posterior fusion system for the treatment of burst fractures

Dominique Pioletti, Arne Christian Vogel, Martin Aeberhard

In the framework of spine traumatology, burst fractures are severe and are often caused by car accidents or by falls. The vertebra breaks under the traumatic compression and pieces of it are shattered in all directions. This type of fracture is often treat ...

2007

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