Association Study of 182 Candidate Genes in Anorexia Nervosa
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PURPOSE OF REVIEW: Rapid expansion of genomic technologies has resulted in an unprecedented ability to interrogate the impact of human genetic variation on disease. HIV-1 infection is a unique model for studying this impact because host genetic variation i ...
Background: There is an ever-increasing volume of data on host genes that are modulated during HIV infection, influence disease susceptibility or carry genetic variants that impact HIV infection. We created GuavaH (Genomic Utility for Association and Viral ...
Motivation: High-throughput sequencing technologies enable the genome-wide analysis of the impact of genetic variation on molecular phenotypes at unprecedented resolution. However, although powerful, these technologies can also introduce unexpected artifac ...
Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have b ...
Objective: Although low weight is a key factor contributing to the high mortality in anorexia nervosa (AN), it is unclear how AN patients sustain low weight compared with bulimia nervosa (BN) patients with similar psychopathology. Studies of genes involved ...
This study uses novel biometric figure rating scales (FRS) spanning body mass index (BMI) 13.8 to 32.2kg/m(2) and BMI 18 to 42kg/m(2). The aims of the study were (i) to compare FRS body weight dissatisfaction and perceptual distortion of women with anorexi ...
Easy accessibility can often lead to over-consumption, as seen in food and alcohol habits. On video on-demand (VOD) services, this has recently been referred to as binge watching, where potentially entire seasons of TV shows are consumed in a single viewin ...
Genome-wide association (GWA) studies aim to dissect the relationship between genotype and phenotype. So far, the focus has been on nuclear genetic determinants as variation in the mitochondrial genome is often low in the study cohorts. Despite this observ ...
Schizophrenia is a chronic disorder determined by a complex mix of genetic and environmental factors. To better understand the contributions of human genetic variation to schizophrenia, we performed a genome-wide association study of a validated endophenot ...
Recent research has indicated a significant mutual influence between food intake and emotional status. Mindfulness has also shown potential in supporting positive changes in dietary habits. In an attempt to improve individual awareness and mindfulness arou ...