Proposal to improve vertebrate cell cultures to establish them as substitutes for the regulatory testing of chemicals and effluents using fish
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A novel system for remote monitoring of metabolism in an animal model is proposed in this paper. The system is obtained by integrating bio-nano-sensors to detect single- metabolites, an electrochemical front-end made with off-the-shelf components, a radio ...
Institute of Electrical and Electronics Engineers2013
To elucidate the effects of chemicals on populations of different species in the environment, efficient testing and modeling approaches are needed that consider multiple stressors and allow reliable extrapolation of responses across species. An adverse out ...
Depression is one of the most disabling medical conditions in the world today, yet its etiologies remain unclear and current treatments are not wholly effective. Animal models are a powerful tool to investigate possible causes and treatments for human dise ...
Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are ...
There is a need for a risk analysis technique specific for academic research laboratories. Since accurate accident data, normally required for quantitative risk analysis, are not available for this environment, expert judgements are often used to describe ...
The use of pesticides may lead to environmental problems, such as surface water pollution, with a risk for aquatic organisms. In the present study, a typical vineyard river of western Switzerland was first monitored to measure discharged loads, identify so ...
Background The Cefic Mixtures Industry Ad-hoc Team (MIAT) has investigated how risks from combined exposures can be effectively identified and managed using concepts proposed in recent regulatory guidance, new advances in risk assessment, and lessons learn ...
At the centre of the research is the preservation of the countryside which is highlighted and studied through an architectural approach which focuses on cabins in the high mountains. The projects must reflect upon territorial, global and sustainable aspect ...
This section reviews the current methodologies that are used for the assessment of the rockfall susceptibility, hazard and risk. Emphasis is given on quantitative methods although qualitative ones are also discussed. The different methodologies are present ...
Accessing 3R information for fundamental research is difficult for many reasons: the titles, abstracts, and author keywords of scientific articles do not contain the terms 3R, Reduce, Refine, Replace, alternatives or replacement. Mesh terms in Pubmed or th ...
