Publication

Intracardiac organization indices for the monitoring of atrial fibrillation

Sarah Volorio
2011
Student project
Abstract

Atrial fibrillation (AF) is the most common arrhythmia observed in clinical practice. It is responsible for about one third of hospitalizations related to problems of arrhythmia. AF is an important clinical entity due to the increased risk of morbidity and mortality. The consequences of AF most frequently found are hemodynamic function impairment (loss of atrial synchronized contraction, irregular and inadequately rapid ventricular rate), atriogenic thromboembolic events and tachycardia induced atrial and ventricular cardiomyopathy. With the present increase of life expectancy, AF prevalence is expected to double in the next fifty years, in particular in western countries. In collaboration with the Division of Cardiology of CHUV, a catheter ablative protocol mainly based on pulmonary vein isolation (PVI) and complex fractionated elctrograms ablations was defined in order to develop new strategies to decrease procedural time and ablation extent. More precisely, surface EGC as intracardiac electrogram (EGM) signals were recorded from different catheters at specific locations before ablation during and after PVI. The purpose of this project is to evaluate the ability of known (AF cycle length) and new intracardiac organization indices based on recorded surface ECGs and EGM signals to monitor AF organization during stepwise ablation of persistent AF.

About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.
Related concepts (35)
Atrial fibrillation
Atrial fibrillation (AF or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. It often begins as short periods of abnormal beating, which become longer or continuous over time. It may also start as other forms of arrhythmia such as atrial flutter that then transform into AF. Episodes can be asymptomatic. Symptomatic episodes may involve heart palpitations, fainting, lightheadedness, shortness of breath, or chest pain.
Atrial flutter
Atrial flutter (AFL) is a common abnormal heart rhythm that starts in the atrial chambers of the heart. When it first occurs, it is usually associated with a fast heart rate and is classified as a type of supraventricular tachycardia. Atrial flutter is characterized by a sudden-onset (usually) regular abnormal heart rhythm on an electrocardiogram (ECG) in which the heart rate is fast. Symptoms may include a feeling of the heart beating too fast, too hard, or skipping beats, chest discomfort, difficulty breathing, a feeling as if one's stomach has dropped, a feeling of being light-headed, or loss of consciousness.
Electrocardiography
Electrocardiography is the process of producing an electrocardiogram (ECG or EKG ), a recording of the heart's electrical activity through repeated cardiac cycles. It is an electrogram of the heart which is a graph of voltage versus time of the electrical activity of the heart using electrodes placed on the skin. These electrodes detect the small electrical changes that are a consequence of cardiac muscle depolarization followed by repolarization during each cardiac cycle (heartbeat).
Show more
Related publications (72)

Finding information-rich electrocardiographic biomarkers to characterize atrial fibrillation.

Anna Mary Mc Cann

Atrial fibrillation (AF) is the most common cardiac arrhythmia; it will affect one in four adults worldwide in their lifetime. AF has serious consequences, including drastically increased risk of stroke. Catheter ablation surgery is an established treatmen ...
EPFL2023

A single-beat algorithm to discriminate farfield from nearfield bipolar voltage electrograms from the pulmonary veins

Jean-Marc Vesin, Adrian Luca, Vincent Schlageter

Background Superimposition of farfield (FF) and nearfield (NF) bipolar voltage electrograms (BVE) complicates the confirmation of pulmonary vein (PV) isolation after catheter ablation of atrial fibrillation. Our aim was to develop an automatic algorithm ba ...
SPRINGER2023

Novel spatiotemporal processing tools for body-surface potential map signals for the prediction of catheter ablation outcome in persistent atrial fibrillation

Jean-Marc Vesin, Adrian Luca, Etienne Pruvot

Background: Signal processing tools are required to efficiently analyze data collected in body-surface-potential map (BSPM) recordings. A limited number of such tools exist for studying persistent atrial fibrillation (persAF). We propose two novel, spatiot ...
FRONTIERS MEDIA SA2022
Show more