Nucleic acid thermodynamicsNucleic acid thermodynamics is the study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA). The melting temperature (Tm) is defined as the temperature at which half of the DNA strands are in the random coil or single-stranded (ssDNA) state. Tm depends on the length of the DNA molecule and its specific nucleotide sequence. DNA, when in a state where its two strands are dissociated (i.e., the dsDNA molecule exists as two independent strands), is referred to as having been denatured by the high temperature.
Impulse responseIn signal processing and control theory, the impulse response, or impulse response function (IRF), of a dynamic system is its output when presented with a brief input signal, called an impulse (δ(t)). More generally, an impulse response is the reaction of any dynamic system in response to some external change. In both cases, the impulse response describes the reaction of the system as a function of time (or possibly as a function of some other independent variable that parameterizes the dynamic behavior of the system).
Semi-simplicityIn mathematics, semi-simplicity is a widespread concept in disciplines such as linear algebra, abstract algebra, representation theory, , and algebraic geometry. A semi-simple object is one that can be decomposed into a sum of simple objects, and simple objects are those that do not contain non-trivial proper sub-objects. The precise definitions of these words depends on the context. For example, if G is a finite group, then a nontrivial finite-dimensional representation V over a field is said to be simple if the only subrepresentations it contains are either {0} or V (these are also called irreducible representations).
