MutationIn biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis).
Point mutationA point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome. Point mutations have a variety of effects on the downstream protein product—consequences that are moderately predictable based upon the specifics of the mutation. These consequences can range from no effect (e.g. synonymous mutations) to deleterious effects (e.g. frameshift mutations), with regard to protein production, composition, and function.
Mutation rateIn genetics, the mutation rate is the frequency of new mutations in a single gene or organism over time. Mutation rates are not constant and are not limited to a single type of mutation; there are many different types of mutations. Mutation rates are given for specific classes of mutations. Point mutations are a class of mutations which are changes to a single base. Missense and Nonsense mutations are two subtypes of point mutations.
EgyptiansEgyptians (مِصرِيُّون, mɪsʕrɪjˈjuːn; مَصرِيِّين, mɑsʕɾɪjˈjiːn; remenkhēmi) are an ethnic group native to the Nile Valley in Egypt. Egyptian identity is closely tied to geography. The population is concentrated in the Nile Valley, a small strip of cultivable land stretching from the First Cataract to the Mediterranean and enclosed by desert both to the east and to the west. This unique geography has been the basis of the development of Egyptian society since antiquity.
EgyptEgypt (مصر ALA mɑsʕr), officially the Arab Republic of Egypt, is a transcontinental country spanning the northeast corner of Africa and the Sinai Peninsula in the southwest corner of Asia. It is bordered by the Mediterranean Sea to the north, the Gaza Strip of Palestine and Israel to the northeast, the Red Sea to the east, Sudan to the south, and Libya to the west. The Gulf of Aqaba in the northeast separates Egypt from Jordan and Saudi Arabia.
Corpus callosumThe corpus callosum (Latin for "tough body"), also callosal commissure, is a wide, thick nerve tract, consisting of a flat bundle of commissural fibers, beneath the cerebral cortex in the brain. The corpus callosum is only found in placental mammals. It spans part of the longitudinal fissure, connecting the left and right cerebral hemispheres, enabling communication between them. It is the largest white matter structure in the human brain, about in length and consisting of 200–300 million axonal projections.
Egyptian languageThe Egyptian language or Ancient Egyptian (r n km.t) is an extinct Afro-Asiatic language that was spoken in ancient Egypt. It is known today from a large corpus of surviving texts which were made accessible to the modern world following the decipherment of the ancient Egyptian scripts in the early 19th century. Egyptian is one of the earliest written languages, first being recorded in the hieroglyphic script in the late 4th millennium BC. It is also the longest-attested human language, with a written record spanning over 4,000 years.
PhenotypeIn genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology (physical form and structure), its developmental processes, its biochemical and physiological properties, its behavior, and the products of behavior. An organism's phenotype results from two basic factors: the expression of an organism's genetic code (its genotype) and the influence of environmental factors. Both factors may interact, further affecting the phenotype.
Egyptian hieroglyphsEgyptian hieroglyphs (ˈhaɪrəˌɡlɪfs, ˈhaɪroʊˌɡlɪfs) were the formal writing system used in Ancient Egypt for writing the Egyptian language. Hieroglyphs combined logographic, syllabic and alphabetic elements, with some 1,000 distinct characters. Cursive hieroglyphs were used for religious literature on papyrus and wood. The later hieratic and demotic Egyptian scripts were derived from hieroglyphic writing, as was the Proto-Sinaitic script that later evolved into the Phoenician alphabet.
History of modern EgyptAccording to most scholars the history of modern Egypt dates from the start of the rule of Muhammad Ali'v in 1805 and his launching of Egypt's modernization project that involved building a new army and suggesting a new map for the country, though the definition of Egypt's modern history has varied in accordance with different definitions of modernity. Some scholars date it as far back as 1516 with the Ottomans' defeat of the Mamlūks in 1516–17.