Lactate dehydrogenaseLactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells. LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NAD+ to NADH and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another. LDH exists in four distinct enzyme classes. This article is specifically about the NAD(P)-dependent L-lactate dehydrogenase. Other LDHs act on D-lactate and/or are dependent on cytochrome c: D-lactate dehydrogenase (cytochrome) and L-lactate dehydrogenase (cytochrome).
Power of a testIn statistics, the power of a binary hypothesis test is the probability that the test correctly rejects the null hypothesis () when a specific alternative hypothesis () is true. It is commonly denoted by , and represents the chances of a true positive detection conditional on the actual existence of an effect to detect. Statistical power ranges from 0 to 1, and as the power of a test increases, the probability of making a type II error by wrongly failing to reject the null hypothesis decreases.
Guinea pigThe guinea pig or domestic guinea pig (Cavia porcellus), also known as the cavy or domestic cavy ('keɪvi ), is a species of rodent belonging to the genus Cavia in the family Caviidae. Breeders tend to use the word cavy to describe the animal, while in scientific and laboratory contexts, it is far more commonly referred to by the common name guinea pig. Despite their common name, guinea pigs are not native to Guinea, nor are they closely related biologically to pigs, and the origin of the name is still unclear.
DiencephalonThe diencephalon (or interbrain) is a division of the forebrain (embryonic prosencephalon). It is situated between the telencephalon and the midbrain (embryonic mesencephalon). The diencephalon has also been known as the 'tweenbrain in older literature. It consists of structures that are on either side of the third ventricle, including the thalamus, the hypothalamus, the epithalamus and the subthalamus. The diencephalon is one of the main vesicles of the brain formed during embryogenesis.
VomitingVomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting.
Superior mesenteric artery syndromeSuperior mesenteric artery (SMA) syndrome is a gastro-vascular disorder in which the third and final portion of the duodenum is compressed between the abdominal aorta (AA) and the overlying superior mesenteric artery. This rare, potentially life-threatening syndrome is typically caused by an angle of 6–25° between the AA and the SMA, in comparison to the normal range of 38–56°, due to a lack of retroperitoneal and visceral fat (mesenteric fat). In addition, the aortomesenteric distance is 2–8 millimeters, as opposed to the typical 10–20.
