Publication

Assessment of adrenoleukodystrophy lesions by high field MRS in non-sedated pediatric patients

Related publications (16)

Transferability of the light-soaking benefits on silicon heterojunction cells to modules

Christophe Ballif, Jonas Geissbühler, Matthieu Despeisse, Mathieu Gérard Boccard, Jean Cattin

We investigate the effect of light soaking and forward electric bias treatment on SHJ solar cells and modules, and in particular the influence of the thermal treatment occurring during lamination. A substantial performance increase is observed after electr ...

2021

Bioengineering human bone marrow models to elucidate the triggers of the stem cell niche

Queralt Vallmajó Martín

The bone marrow (BM) microenvironment, or niche, significantly affects behaviors of its resident stem cell populations. Disruptions in the BM niche contribute to a number of severe clinical pathologies. Discovery of novel therapeutic strategies for BM-rela ...

EPFL2019

Development of a nano-adjuvant cancer vaccine and its evaluation for melanoma in combination with radiotherapy

Sylvie Hauert

Cancer is the second leading cause of death in the world and melanoma is the deadliest type of skin cancer. Although surgery, radiotherapy and chemotherapy are still standard treatments, the discovery of the role played by the immune system in cancer has a ...

EPFL2018

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF(high) neutrophils

Etienne Meylan, Ferdinando Pucci, Julien Robert Rémi Faget

Bone marrow-derived myeloid cells can accumulate within tumors and foster cancer outgrowth. Local immune-neoplastic interactions have been intensively investigated, but the contribution of the systemic host environment to tumor growth remains poorly unders ...

Amer Assoc Advancement Science2017

Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance

Freddy Radtke

Host responses to chemotherapy can induce resistance mechanisms that facilitate tumor regrowth. To determine the contribution of bone marrow-derived cells (BMDCs), we exposed tumor-bearing mice to chemotherapeutic agents and evaluated the influx and contri ...

American Society of Hematology2013

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

Douglas Hanahan

Mutationally corrupted cancer (stem) cells are the driving force of tumor development and progression. Yet, these transformed cells cannot do it alone. Assemblages of ostensibly normal tissue and bone marrow-derived (stromal) cells are recruited to constit ...

Elsevier2012

Gene Expression Profile of Peripheral Blood Lymphocytes from Renal Cell Carcinoma Patients Treated with IL-2, Interferon-α and Dendritic Cell Vaccine

Benita Wolf

Lymphocytes are a key component of the immune system and their differentiation and function are directly influenced by cancer. We examined peripheral blood lymphocyte (PBL) gene expression as a biomarker of illness and treatment effect using the Affymetrix ...

Public Library of Science2012

Interactions between cancer stem cells and their niche govern metastatic colonization

Albert Santamaria Martinez, Ilaria Malanchi, Hans-Anton Lehr

Metastatic growth in distant organs is the major cause of cancer mortality. The development of metastasis is a multistage process with several rate-limiting steps. Although dissemination of tumour cells seems to be an early and frequent event, the successf ...

2012

Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration

Matthias Lütolf, Philipp Sebastian Lienemann, Martin Ehrbar

The regeneration of large bone defects caused by trauma or disease remains a significant clinical problem. Although osteoinductive growth factors such as bone morphogenetic proteins have entered clinics, transplantation of autologous bone remains the gold ...

Elsevier Science Bv2012

The Cell Differentiation Status Influences the Outcome of Notch-Induced Malignancy

Caroline Poisson

The Notch signaling cascade is a well conserved pathway that regulates many aspects of embryonic development and plays a crucial role in the differentiation process and tissue homeostasis in multiple organs of adult species. Several human pathological diso ...

EPFL2011

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