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Alzheimer's Disease-Linked Mutations in Presenilin-1 Result in a Drastic Loss of Activity in Purified gamma-Secretase Complexes

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Alzheimer's Disease-Linked Mutations in Presenilin-1 Result in a Drastic Loss of Activity in Purified gamma-Secretase Complexes

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Identification of new Presenilin-1 phosphosites: implication for gamma-secretase activity and A beta production

The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-beta peptides

New Insights Into Amyloid Formation and Structure by Innovative Atomic Force Microscopy Methods

Real-time Protein Aggregation Monitoring with a Bloch Surface Wavebased Approach

Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production

The Role of γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of γ-Secretase Activity and Amyloid-β Generation

Real-time Amyloid Aggregation Monitoring with a Photonic Crystal-based Approach

Novel Mechanistic Insight into the Molecular Basis of Amyloid Polymorphism and Secondary Nucleation during Amyloid Formation

Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa

Development of a Small D-Enantiomeric Alzheimer's Amyloid-beta Binding Peptide Ligand for Future In Vivo Imaging Applications