Mesenchymal stem cells restore cortical rewiring after neonatal ischemia in mice
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This paper presents the concept and initial results of a novel approach for robot assisted sensorimotor training in stroke rehabilitation. It is based on a brain-body-robot interface (B 2RI), combining both neural and physiological recordings, that detects ...
Intrauterine infection and inflammation are major reasons for preterm birth. The switch from placenta-mediated to lung-mediated oxygen supply during birth is associated with a sudden rise of tissue oxygen tension that amounts to relative hyperoxia in prete ...
Brain imaging has shown altered corpus callosum (CC) morphology in patients with Gilles de la Tourette syndrome (GTS). Yet it is unclear whether these morphological changes are associated with altered interhemispheric interactions. Here, we combined transc ...
A review of published brain-damaged patients showing delusional beliefs concerning the contralesional side of the body (somatoparaphrenia) is presented. Somatoparaphrenia has been reported, with a few exceptions, in right-brain-damaged patients, with motor ...
The discovery of the RNA interference (RNAi) pathway in plants in the early 90's and the subsequent demonstration of its presence in mammalian cells in 2001 were a major breakthrough in biological research. Indeed it was quickly realized that this highly s ...
The most general and striking evidence related with brain injury is that of the restoration of function. Recovery of motor and somatosensory functions has shown to commonly occur after stroke, but not all individuals show improvement. Clinical studies have ...
The hippocampus is injured in both hypoxia-ischemia (HI) and perinatal iron deficiency that are co-morbidities in infants of diabetic mothers and intrauterine growth restricted infants. We hypothesized that preexisting perinatal iron deficiency predisposes ...
MRI tractography is the mapping of neural fiber pathways based on diffusion MRI of tissue diffusion anisotropy. Tractography based on diffusion tensor imaging (DTI) cannot directly image multiple fiber orientations within a single voxel. To address this li ...
Neocortical function and malfunction depends critically on a spectrum of inhibitory interneurons. To gain novel insight in normal brain function and mechanisms leading to diseases, such as epilepsy or schizophrenia, the knowledge about the specific functio ...
Both a large lesion volume and abnormalities in diffusion tensor imaging are independently associated with a poor prognosis after cerebral infarctions. Therefore, we assume that they are associated. This study assessed the associations between lesion volum ...