Publication
Virus inactivation mechanisms: impact of disinfectants on virus function and structural integrity
Related publications (51)
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Chemical oxidation has been applied in municipal water treatment for more than a century, initially for disinfection. In the early decades, chlorine disinfection was adopted in the fight against waterborne disease. However, the oxidative properties of chlo ...
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Chemical oxidants including ozone (O3), chlorine (HOCl/OCl-) and chlorine dioxide (ClO2) are applied for disinfection of drinking water. To cope with water scarcity and the increased risks associated with the presence of micropollutants, water treatment sy ...
EPFL2023Susceptibility of enveloped and non-enveloped viruses to ultraviolet light-emitting diode (UV-LED) irradiation and implications for virus inactivation mechanisms
Ultraviolet (UV) light-emitting diodes (UV-LEDs), a disinfection technology, efficiently inactivate pathogens in water. However, the assessment of UV-LED treatment and the mechanisms of UV inactivation on viruses (especially enveloped viruses) are limited. ...
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Iodine is a naturally-occurring halogen in natural waters generally present in concentrations between 0.5 and 100 mu g L-1. During oxidative drinking water treatment, iodine-containing disinfection by-products (I-DBPs) can be formed. The formation of I-DBP ...
PERGAMON-ELSEVIER SCIENCE LTD2022Inputs of disinfection by-products to the marine environment from various industrial activities: Comparison to natural production
Oxidative treatment of seawater in coastal and shipboard installations is applied to control biofouling and/or minimize the input of noxious or invasive species into the marine environment. This treatment allows a safe and efficient operation of industrial ...
PERGAMON-ELSEVIER SCIENCE LTD2022Genotype-Dependent Kinetics of Enterovirus Inactivation by Free Chlorine and Ultraviolet (UV) Irradiation
Inactivation kinetics of enterovirus by disinfection is often studied using a single laboratory strain of a given genotype. Environmental variants of enterovirus are genetically distinct from the corresponding laboratory strain, yet it is poorly understood ...
2022High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections
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Viruses are genetically and structurally diverse, and outnumber cells by orders of magnitude. They can cause acute and chronic infections, suppress, or exacerbate immunity, or dysregulate survival and growth of cells. To identify chemical agents with pro- ...
2022Presence of sub-inhibitory concentrations of quaternary ammonium compounds in water: effects on bacteria and their inactivation by ozone and monochloramine
Disinfection agents have been present in our daily lives for several decades in detergents or in personal care products, where their role is to prevent the spread of pathogenic microor-ganisms. One of the largest class of disinfection agents is quaternary ...
EPFL2021Update on Interfacial Charge Transfer (IFTC) Processes on Films Inactivating Viruses/Bacteria under Visible Light: Mechanistic Considerations and Critical Issues
This review presents an update describing binary and ternary semiconductors involving interfacial charge transfer (IFCT) in composites made up by TiO2, CuO, Ag2O and Fe2O3 used in microbial disinfection (bacteria and viruses). The disinfection mechanism, ...
2021Adaptation of Human Enterovirus to Warm Environments Leads to Resistance against Chlorine Disinfection
Tamar Kohn, Anna Carratala Ripolles, Virginie Bachmann, Timothy R. Julian
Sunlight, temperature, and microbial grazing are among the environmental factors promoting the inactivation of viral pathogens in surface waters. Globally, these factors vary across time and space. The persistence of viral pathogens, and ultimately their e ...
2020