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Long-term Biosensors for Metabolite Monitoring by using Carbon Nanotubes

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Direct growth of nanotubes and graphene nanoflowers on electrochemical platinum electrodes

Giovanni De Micheli, László Forró, Sandro Carrara, Arnaud Magrez, Federico Matteini, Irene Taurino

Multi-walled carbon nanotubes and graphene nanoflowers were grown by a catalytic chemical vapor deposition process on metal surfaces. Electrodeposition was used as a versatile technique to obtain three different iron catalyst coatings on platinum microelec ...

2013

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Cell analysis requires increasingly more complex equipment to investigate cellular and molecular mechanisms. The goal of the present research is to develop a platform of integrated amperometric biosensors to better understand biological processes by real-t ...

2012

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For diagnostic and therapeutic purposes an accurate determination of multiple metabolites is often required. Amperometric devices are attractive tools to quantify biological compounds due to the direct conversion of a biochemical event to a current. This r ...

2012

Highly Sensitive Carbon Nanotube-Based Sensing for Lactate and Glucose Monitoring in Cell Culture

Giovanni De Micheli, Sandro Carrara, Cristina Boero, Giovanna Del Vecchio

Monitoring of metabolic compounds in cell cultures can provide real-time information of cell line status. This is particularly important in those lines not fully known, as the case of embryonic and mesenchymal cells. On the other hand, such approach can pa ...

Institute of Electrical and Electronics Engineers2011

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Amperometric biosensors are complex systems and they require a combination of technologies for their development. The aim of the present work is to exploit existing technologies for new purposes in order to develop nanostructured biosensors for the real-ti ...

2011

Development of a contactless capacitive immunosensor

Brice Perruche

In the present work, a label-free, contactless and capacitive immunosensor is developed using impedance spectroscopy, in the aim to perform low-cost immunoassays. Chapter 1 puts this work in perspective with some existing techniques, while a presentation o ...

EPFL2011

The dispersion of highly hydrophobic carbon materials such as carbon nanotubes in biological media is a challenging issue. Indeed, the nonspecific adsorption of proteins occurs readily when the nanotubes are introduced in biological media; therefore, a met ...

2011

Continuous-flow multi-analyte biosensor cartridge with controllable linear response range

Nico de Rooij, Peter Van der Wal, Olivier Frey, Sara Talaei

This article presents the design and fabrication of a microfluidic biosensor cartridge for the continuous and simultaneous measurement of biologically relevant analytes in a sample solution. The biosensor principle is based on the amperometric detection of ...

Royal Society of Chemistry2010

Modified surface

Michael Graetzel, Shaik Mohammed Zakeeruddin, Péter Kalman Péchy

The present invention relates to modified surfaces. The surfaces comprise an inorganic material on which a phosphinic acid derivative is adsorbed. The phosphinic acid thus turns out to be a new anchoring group useful for surface derivatisation. The inventi ...

2010

Electrochemical reactions and ionization processes

Hubert Girault, Niels Erik Lion, Liang Qiao, Michel Prudent, Hongyan Bi, Mélanie Abonnenc

Electrochemical or photo-electrochemical reactions in both electrospray ionization and laser desorption ionization are discussed stressing the role of the electrode reaction in influencing the ionization process. In particular, upon application of a high v ...

IM Publications2010