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Highly efficient production of the Alzheimer's γ-Secretase integral membrane protease complex by a multi-gene stable integration approach

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Highly efficient production of the Alzheimer's γ-Secretase integral membrane protease complex by a multi-gene stable integration approach

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A novel cell-based sensor detecting the activity of individual basic proprotein convertases

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

A Universal Assay for Aminopeptidase Activity and Its Application for Dipeptidyl Peptidase-4 Drug Discovery

Multimodal imaging and high-throughput image-processing for drug screening on living organisms on-chip

Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands

Design and validation of bioorthogonal probes for cellular disease models

Advancing Drug Discovery via Artificial Intelligence

Breaking the Fourth Wall: Modulating Quaternary Associations for Protein Regulation and Drug Discovery

A microfluidics platform for combinatorial drug screening on cancer biopsies

Discovery of novel competitive dihydropteridine reductase inhibitors via high throughput screening and their effect on metabolic pterin balance of fibroblast.