Investigation of field and diffusion time dependence of the diffusion-weighted signal at ultrahigh magnetic fields
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We enable the estimation of the per-axon axial diffusivity from single encoding, strongly diffusion-weighted, pulsed gradient spin echo data. Additionally, we improve the estimation of the per-axon radial diffusivity compared to estimates based on spherica ...
Magnonics is an exciting and rapidly growing field revolving around the study and manipulation of magnons, the low-lying collective excitations of magnetically ordered systems. This field has emerged in response to both fundamental physics interests and th ...
High temperature superconducting (HTS) materials have the potential to generate a magnetic field beyond the level obtainable with low temperature superconducting (LTS) materials. This review reports on past and present R&D on HTS cables and conductors for ...
Axonal conduction velocity, which ensures efficient function of the brain network, is related to axon diameter. Noninvasive, in vivo axon diameter estimates can be made with diffusion magnetic resonance imaging, but the technique requires three-dimensional ...
The objective of this thesis is the development of high-field and high-current joints between Nb3Sn cables for superconducting coils. The main fields of application are high energy physics (HEP) and thermonuclear fusion. In this thesis, the focus is on Win ...
Diffusion MRI (dMRI) of the developing brain can provide valuable insights into the white matter development. However, slice thickness in fetal dMRI is typically high (i.e., 3-5 mm) to freeze the in-plane motion, which reduces the sensitivity of the dMRI s ...
Tractography is the only non-invasive technique which is used to reconstruct the white mat- ter structural connectivity of the human brain. It relies on a specific Magnetic Resonance Imaging (MRI) acquisition, called diffusion MRI, which is sensitive to th ...
The anisotropy of brain white matter microstructure manifests itself in orientational-dependence of various MRI contrasts, and can result in significant quantification biases if ignored. Understanding the origins of this orientation-dependence could enhanc ...
Beta amyloid (A beta) accumulation is the earliest pathological marker of Alzheimer's disease (AD), but early AD pathology also affects white matter (WM) integrity. We performed a cross-sectional study including 44 subjects (23 healthy controls and 21 mild ...
The distribution of axon diameters (ADD) is an important white matter feature: it influences action potential speed, it has been shown to evolve during development, and also to be affected during pathological processes. Diffusion Magnetic Resonance Imaging ...