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Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production

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Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production

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The FDA-approved natural product dihydroergocristine reduces the production of the Alzheimer's disease amyloid-beta peptides

Perturbations of the Straight Transmembrane alpha-Helical Structure of the Amyloid Precursor Protein Affect Its Processing by gamma-Secretase

Real-time Protein Aggregation Monitoring with a Bloch Surface Wavebased Approach

The H50Q Mutation Enhances alpha-Synuclein Aggregation, Secretion, and Toxicity

Real-time protein aggregation monitoring with a Bloch surface wave-based approach

The Role of γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of γ-Secretase Activity and Amyloid-β Generation

Real-time Amyloid Aggregation Monitoring with a Photonic Crystal-based Approach

Alzheimer's Disease-Linked Mutations in Presenilin-1 Result in a Drastic Loss of Activity in Purified gamma-Secretase Complexes

Development of a Small D-Enantiomeric Alzheimer's Amyloid-beta Binding Peptide Ligand for Future In Vivo Imaging Applications

Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa