Publication
Two-photon microscopy of the mouse cochlea in situ for cellular diagnosis
Related publications (37)
Auditory externalization in hearing-impaired listeners with remote microphone systems for hearing aids
Hervé Lissek, Gilles André Courtois, Vincent Pierre Olivier Grimaldi
The auditory system enables listeners to estimate the localization of auditory events resorting notablyto individual binaural cues and room reflections reaching the eardrum. For hearing-impaired listenersusing hearing aids, those cues are possibly distorte ...
Canadian Acoustical Association2019Imaging hair cells through laser-ablated cochlear bone
Demetri Psaltis, Ye Pu, Marilisa Romito
We report an innovative technique for the visualization of cells through an overlying scattering medium by combining femtosecond laser bone ablation and two-photon excitation fluorescence (TPEF) microscopy. We demonstrate the technique by imaging hair cell ...
OPTICAL SOC AMER2019Bulged Eardrum Detection From 3D Data
Pascal Frossard, Ivana Tosic, Sofia Karygianni
Bulging is a medical characteristic of the eardrum that is crucial for the diagnosis of acute otitis media. This work proposes a novel classification method for distinguishing bulged eardrums from non-bulged ones. The method uses novel key features extract ...
IEEE2018Effects of Binaural Spatialization in Wireless Microphone Systems for Hearing Aids on Normal-Hearing and Hearing-Impaired Listeners
Hervé Lissek, Xavier Gigandet, Gilles André Courtois
Little is known about the perception of artificial spatial hearing by hearing-impaired subjects. The purpose of this study was to investigate how listeners with hearing disorders perceived the effect of a spatialization feature designed for wireless microp ...
2018Subjective evaluation of a spatialization feature for hearing aids by normal-hearing and hearing-impaired subjects
Hervé Lissek, Xavier Gigandet, Gilles André Courtois
Remote microphone systems significantly improve speech intelligibly performance offered by hearing aids. The voice of the speaker(s) is captured close to the mouth by a microphone, then wirelessly sent to the hearing aids. However, the sound is rendered in ...
AES2018High-Resolution fMRI of Auditory Cortical Map Changes in Unilateral Hearing Loss and Tinnitus
Dimitri Nestor Alice Van De Ville, Melissa Saenz, Wietske Van der Zwaag, Naghmeh Ghazaleh, Stephanie Clarke
Animal models of hearing loss and tinnitus observe pathological neural activity in the tonotopic frequency maps of the primary auditory cortex. Here, we applied ultra high-field fMRI at 7 T to test whether human patients with unilateral hearing loss and ti ...
Springer Verlag2017Neuroimaging of human auditory cortex
Modern neuroimaging technologies provide us with non-invasive methods for study- ing structure and function, and plasticity of the human auditory cortex. Here we have acquired high spatial resolution functional magnetic resonance imaging (fMRI) data of the ...
EPFL2017Optical proximity sensing system for atraumatic cochea implant surgery
Demetri Psaltis, Christophe Moser, Ye Pu
The design of a proximity sensor to be integrated into cochlea implants is described. The sensor allows the anticipation of contact between the cochlear implant and intracochlear structures, including the cochlear canal wall and basilar membrane, providing ...
2017Surgical Anatomy of the Human Round Window Region: Implication for Cochlear Endoscopy Through the External Auditory Canal
Demetri Psaltis, Simon Nessim Henein
Objective: To enable development of an endoscope for cellular-level optical imaging of the inner ear. Study Design: A prospective study of 50 cadaveric human temporal bones to define detailed surgical anatomy of the round window (RW) region and the range o ...
Lippincott, Williams & Wilkins2016Human audiometric thresholds do not predict specific cellular damage in the inner ear
Introduction: As otology enters the field of gene therapy and human studies commence, the question arises whether audiograms - the current gold standard for the evaluation of hearing function - can consistently predict cellular damage within the human inne ...
Elsevier2016