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Mechanisms of resistance to BCR-ABL and other kinase inhibitors

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Mechanisms of resistance to BCR-ABL and other kinase inhibitors

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Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1(T315I) and BCR-ABL1(T315I-E255K)

Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity

Allosteric kinase inhibitors

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase

Differential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics

Allosteric regulation and targeting of Abl SH2-kinase interface and other cytoplasmic tyrosine kinases

Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface

HRD Motif as the Central Hub of the Signaling Network for Activation Loop Autophosphorylation in Abl Kinase