Dissipation as variable in cartilage mechanobiology
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Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
Synoyial joints articulate in a lubricating environment, the system providing for smooth articulation. The articular cartilage overlying the bone consists of a network of collagen fibres. This network is essential to cartilage integrity, suffering damage i ...
Micro Proton Induced X-ray Emission (mu-PIXE) analysis has been employed herein in investigating and quantifying the distribution of a number of essential elements in thin human diseased articular cartilage sections affected by osteoarthritis (OA). Various ...
The aim of this contribution is to review the application of thermodynamics to live cultures of microbial and other cells and to explore to what extent this may be put to practical use. A major focus is on energy dissipation effects in industrially relevan ...
In the context of coupling methods that match molecular dynamics with finite elements, we focus on the finite temperature and heat rates treatment done by Bridging Domain approaches. The energy dissipation occurring due to the projection of the fine scale ...
In this work a 3D musculoskeletal model of the knee joint, that can simulate a squat movement, has been developed. Such a model would be useful to understand the biomechanics of the knee. The model consisted of all the the bones with their articular surfac ...
Self excited instabilities or oscillations of a cavitating full load vortex rope occur due to an interaction between the gas volume and the acoustic waves. From the onset of the oscillations, the amplitudes grow until they reach a maximum, called the “limi ...
Osteoarthritis (OA) is one of the most common causes of pain and disability. Currently, non-surgical treatment is limited to analgesic and anti-inflammatory drugs, which are not capable of either modifying the disease process or regenerate damaged parts in ...
Nowadays, cartilage repair is a worldwide centre of interest due to the low potential of cartilage to heal spontaneously and the increasing number of patients around the world. One of the techniques to treat cartilage defect is to use autologous human seru ...
The extracellular matrix of dense, avascular tissues presents a barrier to entry for polymer-based therapeutics, such as drugs encapsulated within polymeric particles. Here, we present an approach by which polymer nanoparticles, suffciently small to enter ...