Seamless Integration of Dose-Response Screening and Flow Chemistry: Efficient Generation of Structure-Activity Relationship Data of β-Secretase (BACE1) Inhibitors
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This paper describes the scientific vision and objectives of the FET Flagship candidate initiative Robot Companions for Citizens. Robot Companions will be a new generation of machines that will primarily help and assist elderly people in activities of dail ...
Rhythmic and discrete movements are frequently considered separately in motor control, probably because different techniques are commonly used to study and model them. Yet, an increasing interest for a comprehensive model for movement generation requires t ...
Driven by the exponentially growing demand for capacity, it is already apparent that the next generation of telecommunication networks will be radically different from previous implementations; coherent detection along with powerful digital signal processi ...
Aim of the study: This work develops a measurement technique for pressure waves in soft tissues. It aims at characterizing, understanding and modeling the generation and propagation of pressure waves in soft tissues, with a view towards medical application ...
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This article reports the design, synthesis and results of first in vitro model studies of a conceptually novel class of polymer therapeutics in which the cargo is attached to a polymer backbone via a noncovalent, biologically inspired coiled coil linker, w ...
The aim of the invention is to propose the generation, verification and denial of an undeniable signature which has a size smaller than the currently available undeniable signatures, i.e. less than 80 bits. This aim is achieved by the method to generate an ...
Due to daylight variability, a design cannot be thoroughly assessed using single-moment simulations, which is why we need dynamic performance metrics like Daylight Autonomy and Useful Daylight Illuminance. Going one step further, the annual variation in pe ...
The X-ray polarization anisotropy of anomalous scattering in crystals of brominated nucleic acids and selenated proteins is shown to have significant effects on the diffraction data collected at an absorption edge. For conventionally collected single- or mu ...
Creating a consistent thermodynamic database is the first step required to perform a process integration study. A method based on the use of data identification and reconciliation has been developed to model the mass and the energy balances of a pulp and p ...
Next Generation Business Handbook offers strategies for the next generation of business success from the best business schools around the world. * Presents fresh ideas from the young, up-and-coming business thinkers and experts from the world's best busine ...