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Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet.Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuati ...
The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data from the Genotype-Tissue Expression (GTEx) project with an a ...
The circadian clock regulates diurnal variations in autonomic thermoregulatory processes such as core body temperature in humans. Thus, we might expect that similar daily fluctuations also characterize human thermal perception, the ultimate role of which i ...
Ray et al. (Reports, 14 February 2020, p. 800) recently claimed temperature-compensated, free-running mRNA oscillations in Bmal1(-/-) liver slices and skin fibroblasts. We reanalyzed these data and found far fewer reproducible mRNA oscillations in this gen ...
In this video, Prof. Marilyne Andersen discusses the many benefits, challenges, promises and ongoing research on daylighting as an essential part of our daily life. The podcast addresses questions of design, comfort, resource efficiency and health by divin ...
Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and-independent mechanisms have provided important insight into neuronal regeneration, however, common denominators underpinning regeneration remain ...
Current methods for near real-time estimation of effective reproduction numbers from surveillance data overlook mobility fluxes of infectors and susceptible individuals within a spatially connected network (the metapopulation). Exchanges of infections amon ...
2023
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Our exposure to light has a key role in regulating our biological clock through a dedicated photoreceptor present in the human eye. Increased awareness to its criticality when it comes to human well-being is urgently needed, as this criticality is potentia ...
SoomeenHahm Design Ltd2021
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Video Abstract Video Abstract: Theory of time delayed genetic oscillations with external noisy regulation We present a general theory of noisy genetic oscillators with externally regulated production rate and multiplicative noise. The observables that char ...
IOP PUBLISHING LTD2021
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We construct reduced order models for two classes of globally coupled multi-component oscillatory systems, selected as prototype models that exhibit synchronization. These are the Kuramoto model, considered both in its original formulation and with a suita ...
