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Publication
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
Mycobacterium goes yeast: Target deconvolution of anti-tuberculosis drugs can be a very challenging task. Here we report a yeast 3-hybrid system that allows promising small molecules to be screened for protein targets of a pathogen in nontoxic yeast cells. The system employs libraries of randomly fragmented bacterial DNA and offers a technically simple alternative approach for target identification. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Christian Heinis, Gerardo Turcatti, Julien Bortoli Chapalay, Alessandro Angelini, Manuel Leonardo Merz, Sevan Mleh Habeshian, Jonathan Patrice Vesin, Mischa Schüttel, Ganesh Kumar Mothukuri, Gontran Sangouard, Cristina Diaz Perlas, Zsolt Bognár