Large-scale in-silico analysis of CSF dynamics within the subarachnoid space of the optic nerve

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Adaptive Finite Elements with Large Aspect Ratio. Application to Aluminium Electrolysis

The goal of this work is to use anisotropic adaptive finite elements for the numerical simulation of aluminium electrolysis. The anisotropic adaptive criteria are based on a posteriori error estimates derived for simplified problems. First, we consider an ...

EPFL2024

CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Ludovic Pierre Gustave Keiser, Laura Desban

The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether and how sensory cells in the central nervous system (CNS) become activated during bacteri ...

CELL PRESS2023

Highly Efficient Miniaturized Magnetorheological Valves Using Electropermanent Magnets

Yves Perriard, Christian Köchli, Sofia Lydia Ntella, Adrien Jean-Michel Thabuis, Kenny Jeanmonod, Bhawnath Tiwari

Fluidic systems enable actuation in various applications, such as automotive, medical, and industrial robotics. Miniaturized valves constitute a fundamental controlling element of modern fluidic systems, intriguing the interest of many researchers. This le ...

2023

Design, computational and experimental investigation of a small-scale turbopump for organic Rankine cycle systems

Jürg Alexander Schiffmann, Sajjad Zakeralhoseini

The hydraulic design, computational analysis, and experimental investigations of a high-speed small-scale turbopump for mobile waste heat recovery applications based on organic Rankine cycle systems are presented in this paper. Such applications demand hig ...

Elsevier2023

Soft bioelectronic technologies for selective and multimodal peripheral nerve interfaces

Valentina Marie Paggi

The peripheral nervous system (PNS) regulates the exchange of sensory information and motor commands between the body and the central nervous system. Further, through the autonomic nervous system, the PNS plays a pivotal role in controlling vital physiolog ...

EPFL2023

Reconstruction of nerve functional topography using recruitment curves enables selective electrical stimulation

Silvestro Micera, Simone Romeni, Bianca Ziliotto

Multi-polar stimulation protocols have been used in the past to increase the selectivity of electrical stimulation of the nervous system. Nonetheless, the number of possible multipolar stimulation protocols is prohibitively large and cannot be explored dur ...

IEEE2023

Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function

Gioele La Manno, Zahra Moslehi, Nina-Lydia Kazakou

The myelinated white matter tracts of the central nervous system (CNS) are essential for fast transmission of electrical impulses and are often differentially affected in human neurodegenerative diseases across CNS region, age and sex. We hypothesize that ...

BMC2023

Rock-Flow Cell Parameters Evaluation Using Ultrasound Doppler Velocimetry

Giovanni De Cesare, Javier Neves da Silva, Andre Luis Stakowian

This work presents a study of two-phase flow generated inside a rock-flow cell setup. It is characterized by a pipe section filled with fluid (oil in our studies) that is put into oscillation around its mass centre by an electric motor. This type of appara ...

2023

A Fast Hybrid Pressure-Correction Algorithm for Simulating Incompressible Flows by Projection Methods

Jiannong Fang

To enforce the conservation of mass principle, a pressure Poisson equation arises in the numerical solution of incompressible fluid flow using the pressure-based segregated algorithms such as projection methods. For unsteady flows, the pressure Poisson equ ...

2023

Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease

Hilal Lashuel, Yogesh Singh Chauhan, Florian Lang, Joan Romani Aumedes, Yogesh Singh

Background Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system, and this progression can be monitored by detecting the accumulation of alpha-Synuclei ...

BMC2023

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Adaptive Finite Elements with Large Aspect Ratio. Application to Aluminium Electrolysis

Paride Passelli

EPFL2024

CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Ludovic Pierre Gustave Keiser, Laura Desban

CELL PRESS2023

Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease

Hilal Lashuel, Yogesh Singh Chauhan, Florian Lang, Joan Romani Aumedes, Yogesh Singh

BMC2023

Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function

Gioele La Manno, Zahra Moslehi, Nina-Lydia Kazakou

BMC2023