Publications related to Hyperpolarized Magnetic Resonance as a Sensitive Detector of Metabolic Function

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Streamline RimNet: Tools for Automatic Classification of Paramagnetic Rim Lesions in MRI of Multiple Sclerosis

Meritxell Bach Cuadra, Cristina Granziera, Francesco La Rosa, Maxence Charles F Wynen

This site provides two software tools related to "RimNet: A deep 3D multimodal MRI architecture for paramagnetic rim lesion assessment in multiple sclerosis" by Barquero et al. NeuroImage: Clinical (2020). People using in part or f ...

Zenodo2023

A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience

Daniel Keller, Andrii Stepaniuk

Neuroscience incorporates knowledge from a range of scales, from single molecules to brain wide neural networks. Modeling is a valuable tool in understanding processes at a single scale or the interactions between two adjacent scales and researchers use a ...

HUMANA PRESS INC2022

ICRF modelling in 2D and 3D magnetic configurations using a hot plasma model

Wilfred Anthony Cooper, Jonathan Graves, Mike Machielsen

The generation of energetic trapped ions is important for experiments investigating their confinement in 3D magnetic fields, for plasma heating, for studies into unwanted drive of instabilities, and improved transport regimes. An effective way to generate ...

2021

Development of novel tools for imaging of metabolic fluxes in vivo

Tamara Maric

Bioluminescent imaging is a powerful technique that enables imaging in living organisms with high sensitivity, low background signal, low cost and without the need for radioactivity. The emitted photons are produced in the oxidation reaction of luciferin c ...

EPFL2020

Modeling chloride transport using travel time distributions at Plynlimon, Wales

Andrea Rinaldo, Paolo Benettin, Gianluca Botter

Here we present a theoretical interpretation of high-frequency, high-quality tracer time series from the Hafren catchment at Plynlimon in mid-Wales. We make use of the formulation of transport by travel time distributions to model chloride transport origin ...

Amer Geophysical Union2015

In-situ photopolymerization and monitoring device for controlled shaping of tissue fillers, replacements or implants

Dominique Pioletti, Christophe Moser, Andreas Schmocker, Azadeh Khoushabi

Photopolymerization is a common tool to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler simply by illumination. Traditionally, photopolymerization has been used ...

Spie-Int Soc Optical Engineering2015

Photopolymerization device for minimally invasive implants: application to nucleus pulposus replacement

Dominique Pioletti, Pierre-Etienne Bourban, Christophe Moser, Andreas Schmocker, Azadeh Khoushabi

Photopolymerization is a common tool to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler. Traditionally, photopolymerization has been used mainly in dentistry. Ov ...

Springer2015

Design of computational retrobiosynthesis tools for the design of de novo synthetic pathways

Vassily Hatzimanikatis, Noushin Hadadi

Designing putative metabolic pathways is of great interest in synthetic biology. Retrobiosynthesis is a discipline that involves the design, evaluation, and optimization of de novo biosynthetic pathways for the production of high-value compounds and drugs ...

Elsevier Sci Ltd2015

Molecular Orbital Gates for Plasmon Excitation

Klaus Kern, Uta Schlickum, Christian Alexander Stephan Dette, Theresa Lutz, Christoph Grosse, Alexander Kabakchiev

Future combinations of plasmonics with nanometer-size electronic circuits require strategies to control the electrical excitation of plasmons at the length scale of individual molecules. A unique tool to study the electrical plasmon excitation with ultimat ...

Amer Chemical Soc2013