DprE1-from the Discovery to the Promising Tuberculosis Drug Target
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Worldwide, tuberculosis (TB) is the leading cause of death due to a single infectious agent, claiming 1.6 million human lives and causing >10 million new cases in 2017 alone, mostly in low-income regions. The intracellular pathogen Mycobacterium tuberculos ...
EPFL2019
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25 years. In this review, we dwell on the various challenges along the journey of bringing a biophysical model from initial design to clinical implementation, identifyi ...
2020
This chapter introduces the readers and users to the goals of the digitally provided index of the compendium Structures of Epic Poetry and the methods used for it. It also expands on the broader applicability of digital methods in view of electronic publis ...
De Gruyter2019
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Connectivity between the hyporheic zone and the flow is essential for the development of benthos and the reproductive success of spawning fish. The infiltration of fine sediment leads to clogging of the riverbed, reducing porosity and vertical water exchan ...
2023
This chapter discusses the Moldovan scientific diaspora made up of students, researchers and those engaged in Professional activities abroad, and their propensity to either return or engage in home-country development initiatives. Moldova has suffered a si ...
Routledge2017
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We report the discovery of benzothiazoles, a novel anti-mycobacterial series, identified from a whole cell based screening campaign. Benzothiazoles exert their bactericidal activity against Mycobacterium tuberculosis (Mtb) through potent inhibition of deca ...
Elsevier2015
Creative and innovative communities, hubs, clusters and industries are supporting and fostering exchange and innovation. China is often perceived as a model for innovation and economic development, countries from the Global South use China as a role model ...
2018
Within the framework of the Post-2015 Development Agenda, discussions on Financing for Development and the future of ODA have intensified recently. Amongst the many financial instruments that are potentially under review, are soft loans. Combining tied aid ...
Semester project to design and develop a display device for use at Musée de l’Elysée to display Lippmann plates. Display platform and light fixtures designed to obtain the full spectrum of Lippmann plates. ...
Broughan, Christine, Graham Steventon, and Lynn Clouder, eds. Global Perspectives on Teaching Excellence: A new era for higher education. Routledge, 2018. ...
