Cognitive Enhancers (Nootropics). Part 3: Drugs Interacting with Targets other than Receptors or Enzymes. Disease-Modifying Drugs. Update 2014
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The enthralling properties of lanthanide luminescence have propelled luminescent probes, tags and materials based on these elements to the forefront of science and technology. In this minireview, attention is focused on the latest innovations and on less-k ...
A review, with refs. When mentioning prokaryotic metabolic engineering, most people will immediately think of Jay Bailey. Jay's contribution to this fast-growing field is evident and familiar to many. Therefore, instead of a detailed tech. review, we attem ...
The existence of a length threshold, of about 35 residues, above which polyglutamine repeats can give rise to aggregation and to pathologies, is one of the hallmarks of polyglutamine neurodegenerative diseases such as Huntington's disease. The reason why s ...
Unique within the field for being written in a tutorial style, this textbook adopts a step-by-step approach to the background needed for understanding a wide range of full-field optical measurement techniques in solid mechanics. This method familiarizes re ...
The correlation between neurodegenerative disease and protein aggregation in the brain has long been recognized, but a causal relationship has not been unequivocally established, in part because a discrete pathogenic aggregate has not been identified. The ...
The integration of sample pretreatment into microfluidic devices represents one of the remaining hurdles towards achieving true miniaturized total analysis systems (μTAS). The challenge is made more complex by the enormous variation in samples to be analyz ...
A review with 15 refs. Directed mol. evolution of enzymes and proteins has emerged as an extremely powerful method to create proteins with novel properties, both for practical applications as well as for mechanistic studies. To demonstrate the underlying p ...
Photodynamic therapy (PDT) is a minimally invasive form of treatment, which is clinically approved for the treatment of angiogenic disorders, including certain forms of cancer and neovascular eye diseases. Although the concept of PDT has existed for a long ...
A brief review with 18 refs. is provided of the principal research and development activities of the Lab. of Polyelectrolytes and BioMacromols. at the Swiss Federal Institute of Technol. These include, in particular, the synthesis of tailor-made polyelectr ...
A review with 51 refs. of the developments leading to the advent of femtochem. is presented, along with the major achievements that have marked the past fifteen years since the birth of the field. [on SciFinder (R)] ...
