Publication

As Time Goes by: KRABs Evolve to KAP Endogenous Retroelements

Didier Trono, Michaël Imbeault
2014
Journal paper

Abstract

Retroelements, constituting about 50% of the human genome, both contribute to its evolution and threaten its integrity and are thus silenced during development. Jacobs et al. (2014) identify sequence-specific KRAB-ZNF proteins that repress subsets of L1 and SVA retrotransposons in humans, highlighting the evolutionary interplay between retroelements and their hosts.

Official source

https://infoscience.epfl.ch/record/204044?ln=en

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As Time Goes by: KRABs Evolve to KAP Endogenous Retroelements

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