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NanoSIMS and Electron Microscopy: A powerful combination in Life Science Research.

Related publications (43)

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Microsecond Time-Resolved Cryo-Electron Microscopy

Oliver Florian Harder

Recently, single-particle cryo-electron microscopy emerged as a technique capable of determining protein structures at near-atomic resolution and resolving protein dynamics with a temporal resolution ranging from second to milliseconds. This thesis describ ...

EPFL2024

In Situ and Time-Resolved Transmission Electron Microscopy of Nanoscale Processes

Chengcheng Yan

Observing the fast dynamics of nanoscale systems is crucial in order to understand and ultimately control their behavior. Characterizing these dynamic processes requires techniques with atomic spatial resolution and a temporal resolution that matches the t ...

EPFL2023

BigDataProcessor2: a free and open-source Fiji plugin for inspection and processing of TB sized image data

Nicolas René Chiaruttini

Modern bioimaging and related areas such as sensor technology have undergone tremendous development over the last few years. As a result, contemporary imaging techniques, particularly electron microscopy (EM) and light sheet microscopy, can frequently gene ...

OXFORD UNIV PRESS2021

Understanding semiconductor nanostructures via advanced electron microscopy and spectroscopy

Reza Zamani

Transmission electron microscopy (TEM) offers an ample range of complementary techniques which are able to provide essential information about the physical, chemical and structural properties of materials at the atomic scale, and hence makes a vast impact ...

IOP PUBLISHING LTD2019

The response of Y2O3 nanoprecipitates in a 1-mu m YBa2Cu3O7-x layer from a superconducting wire Ag/YBCO/buffer metal oxides/Hastelloy to 107 MeV Kr and 167 MeV Xe ion irradiation was investigated using a combination of transmission electron microscopy, dif ...

2018

Miniaturizing EM Sample Preparation: Opportunities, Challenges, and "Visual Proteomics"

Henning Paul-Julius Stahlberg, Anastasia Syntychaki

This review compares and discusses conventional versus miniaturized specimen preparation methods for transmission electron microscopy (TEM). The progress brought by direct electron detector cameras, software developments and automation have transformed tra ...

Wiley-Blackwell2018

We present a new software package called Focus that interfaces cryo-transmission electron microscopy (cryo-EM) data collection with computer image processing. Focus creates a user-friendly environment to import and manage data recorded by direct electron d ...

Elsevier BV2017

Blotting-free and lossless cryo-electron microscopy grid preparation from nanoliter-sized protein samples and single-cell extracts

Henning Paul-Julius Stahlberg, Anastasia Syntychaki

We present a sample preparation method for cryo-electron microscopy (cryo-EM) that requires only 320 nL of sample to prepare a cryo-EM grid, depending on the protocol used. The sample is applied and spread on the grid by a microcapillary. The procedure doe ...

Elsevier BV2017

Electron microscopy (EM) entered a new era with the emergence of direct electron detectors and new nanocrystal electron diffraction methods. However, sample preparation techniques have not progressed and still suffer from extensive blotting steps leading t ...

American Chemical Society (ACS)2016

Hardness and microstructural variation of Al-Mg-Mn-Sc-Zr alloy

Pierre Burdet

Variations of Vickers hardness were observed in Al-Mg-Mn alloy and Al-Mg-Mn-Sc-Zr alloy at different ageing times, ranging from a peak value of 81.2 HV at 54 ks down to 67.4 HV at 360 ks, below the initial hardness value, 71.8 HV at 0 ks for the case of Al ...

Pergamon-Elsevier Science Ltd2016