A three-dimensional self-opening intraneural peripheral interface (SELINE)
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The treatment of disorders of the nervous system poses a major clinical challenge. Development of neuromodulation (i.e., interfacing electronics to nervous tissue to modulate its function) has provided patients with neuronal-related deficits a new tool to ...
Neurotechnology is the application of scientific knowledge to the practical purpose of understanding, interacting and/or repairing the brain or, in a broader sense, the nervous system. The development of novel approaches to decode functional information fr ...
Gene-based delivery can establish a sustained supply of therapeutic proteins within the nervous system. For diseases characterized by extensive CNS and peripheral nervous system (PNS) involvement, widespread distribution of the exogenous gene may be requir ...
Peripheral nerve regeneration following injury occurs spontaneously, but many of the processes require metabolic energy. The mechanism of energy supply to axons has not previously been determined. In the central nervous system, monocarboxylate transporter ...
Background: The restoration of complex hand functions by creating a novel bidirectional link between the nervous system and a dexterous hand prosthesis is currently pursued by several research groups. This connection must be fast, intuitive, with a high su ...
This article illustrates the development and preliminary results of SELINE, a self-opening neural interface. The advantages of this innovative neural interface are: higher selectivity due to its three-dimensional structure and efficient anchorage system to ...
The interest in new materials and their application in the neuroscience are growing incredibly fast. Current research interests are increasingly focusing on new artificial materials and their direct effects on the central nervous systems so that it would b ...
The ability of tracking peripheral nerves in foot could be of great benefit for a number of investigations, which include traumas, diabetes and infections. Previous approaches to nerve tracking have employed diffusion tensor imaging (DTI, [1, 2]), which is ...
This paper describes how specimens of nervous tissue can be prepared for successful imaging in X-ray Micro Computed Tomography (μCT), and how this method can be used to study the integration of nervous tissue into a polymeric scaffold. The sample preparati ...
Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged alon ...