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Continuous Localization Using Sparsity Constraints for High-Density Super-Resolution Microscopy

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Advice (complexity)

In computational complexity theory, an advice string is an extra input to a Turing machine that is allowed to depend on the length n of the input, but not on the input itself. A decision problem is in the complexity class P/f(n) if there is a polynomial time Turing machine M with the following property: for any n, there is an advice string A of length f(n) such that, for any input x of length n, the machine M correctly decides the problem on the input x, given x and A.

Spectral density estimation

In statistical signal processing, the goal of spectral density estimation (SDE) or simply spectral estimation is to estimate the spectral density (also known as the power spectral density) of a signal from a sequence of time samples of the signal. Intuitively speaking, the spectral density characterizes the frequency content of the signal. One purpose of estimating the spectral density is to detect any periodicities in the data, by observing peaks at the frequencies corresponding to these periodicities.

Sparse dictionary learning

Sparse dictionary learning (also known as sparse coding or SDL) is a representation learning method which aims at finding a sparse representation of the input data in the form of a linear combination of basic elements as well as those basic elements themselves. These elements are called atoms and they compose a dictionary. Atoms in the dictionary are not required to be orthogonal, and they may be an over-complete spanning set. This problem setup also allows the dimensionality of the signals being represented to be higher than the one of the signals being observed.

Dirichlet distribution

In probability and statistics, the Dirichlet distribution (after Peter Gustav Lejeune Dirichlet), often denoted , is a family of continuous multivariate probability distributions parameterized by a vector of positive reals. It is a multivariate generalization of the beta distribution, hence its alternative name of multivariate beta distribution (MBD). Dirichlet distributions are commonly used as prior distributions in Bayesian statistics, and in fact, the Dirichlet distribution is the conjugate prior of the categorical distribution and multinomial distribution.

Autoencoder

An autoencoder is a type of artificial neural network used to learn efficient codings of unlabeled data (unsupervised learning). An autoencoder learns two functions: an encoding function that transforms the input data, and a decoding function that recreates the input data from the encoded representation. The autoencoder learns an efficient representation (encoding) for a set of data, typically for dimensionality reduction. Variants exist, aiming to force the learned representations to assume useful properties.

Wavelet

A wavelet is a wave-like oscillation with an amplitude that begins at zero, increases or decreases, and then returns to zero one or more times. Wavelets are termed a "brief oscillation". A taxonomy of wavelets has been established, based on the number and direction of its pulses. Wavelets are imbued with specific properties that make them useful for signal processing. For example, a wavelet could be created to have a frequency of Middle C and a short duration of roughly one tenth of a second.

Beta distribution

In probability theory and statistics, the beta distribution is a family of continuous probability distributions defined on the interval [0, 1] or (0, 1) in terms of two positive parameters, denoted by alpha (α) and beta (β), that appear as exponents of the variable and its complement to 1, respectively, and control the shape of the distribution. The beta distribution has been applied to model the behavior of random variables limited to intervals of finite length in a wide variety of disciplines.

Sparse approximation

Sparse approximation (also known as sparse representation) theory deals with sparse solutions for systems of linear equations. Techniques for finding these solutions and exploiting them in applications have found wide use in , signal processing, machine learning, medical imaging, and more. Consider a linear system of equations , where is an underdetermined matrix and . The matrix (typically assumed to be full-rank) is referred to as the dictionary, and is a signal of interest.

Linear approximation

In mathematics, a linear approximation is an approximation of a general function using a linear function (more precisely, an affine function). They are widely used in the method of finite differences to produce first order methods for solving or approximating solutions to equations. Given a twice continuously differentiable function of one real variable, Taylor's theorem for the case states that where is the remainder term.

Taylor's theorem

In calculus, Taylor's theorem gives an approximation of a -times differentiable function around a given point by a polynomial of degree , called the -th-order Taylor polynomial. For a smooth function, the Taylor polynomial is the truncation at the order of the Taylor series of the function. The first-order Taylor polynomial is the linear approximation of the function, and the second-order Taylor polynomial is often referred to as the quadratic approximation.