The invention concerns a method for screening compound interaction with transmembrane receptors involved in cellular signal transduction, preferably with G protein coupled receptors, by adding the compound to be analyzed into a medium comprising native inverted vesicles with at least one said transmembrane receptor whose native intracellular side is located on the outer surface of the inverted vesicle.
Patrick Daniel Barth, Mahdi Hijazi, Aurélien Laurent Jean-Charles Oggier, Dániel Kéri
Bruno Emanuel Ferreira De Sousa Correia, Pablo Gainza Cirauqui