Complete androgen insensitivity syndromeComplete androgen insensitivity syndrome (CAIS) is an AIS condition that results in the complete inability of the cell to respond to androgens. As such, the insensitivity to androgens is only clinically significant when it occurs in individuals who are exposed to significant amounts of testosterone at some point in their lives. The unresponsiveness of the cell to the presence of androgenic hormones prevents the masculinization of male genitalia in the developing fetus, as well as the development of male secondary sexual characteristics at puberty, but does allow, without significant impairment, female genital and sexual development in those with the condition.
Selective androgen receptor modulatorSelective Androgen Receptor Modulators or SARMs are a class of androgen receptor ligands that were developed with the intention of maintaining some of the desirable effects of androgens, such as preventing osteoporosis and muscle loss while reducing risks of undesirable conditions such as prostate cancer. In the late 1990s, the first nonsteroidal SARM, an analog of bicalutamide, was discovered at Imperial Chemical Industries.
Biological specificityBiological specificity is the tendency of a characteristic such as a behavior or a biochemical variation to occur in a particular species. Biochemist Linus Pauling stated that "Biological specificity is the set of characteristics of living organisms or constituents of living organisms of being special or doing something special. Each animal or plant species is special. It differs in some way from all other species...biological specificity is the major problem about understanding life.
BurrowA burrow is a hole or tunnel excavated into the ground by an animal to construct a space suitable for habitation or temporary refuge, or as a byproduct of locomotion. Burrows provide a form of shelter against predation and exposure to the elements, and can be found in nearly every biome and among various biological interactions. Many animal species are known to form burrows. These species range from small invertebrates, such as the Corophium arenarium, to very large vertebrate species such as the polar bear.
MedrogestoneMedrogestone, sold under the brand name Colprone among others, is a progestin medication which has been used in menopausal hormone therapy and in the treatment of gynecological disorders. It is available both alone and in combination with an estrogen. It is taken by mouth. Medrogestone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has weak antiandrogenic, glucocorticoid, and antimineralocorticoid activity and no other important hormonal activity.
Infanticide (zoology)In animals, infanticide involves the intentional killing of young offspring by a mature animal of the same species. Animal infanticide is studied in zoology, specifically in the field of ethology. Ovicide is the analogous destruction of eggs. The practice has been observed in many species throughout the animal kingdom, especially primates (primate infanticide) but including microscopic rotifers, insects, fish, amphibians, birds and mammals. Infanticide can be practiced by both males and females.
MaléMalé (ˈmɑːleɪ, ˈmaːle; މާލެ) is the capital and most populous city of the Maldives. With a population of 252,768 including other districts and an area of , it is also one of the most densely populated cities in the world. The city is geographically located in the southern edge of North Malé Atoll (Kaafu Atoll). Administratively, the city consists of a central island, an airport island, and four other islands presided over by the Malé City Council. Traditionally it was the King's Island, from where the ancient royal dynasties ruled and where the palace was located.
LizardLizards are a widespread group of squamate reptiles, with over 7,000 species, ranging across all continents except Antarctica, as well as most oceanic island chains. The group is paraphyletic since it excludes the snakes and Amphisbaenia, although some lizards are more closely related to these two excluded groups than they are to other lizards. Lizards range in size from chameleons and geckos a few centimeters long to the 3-meter-long Komodo dragon. Most lizards are quadrupedal, running with a strong side-to-side motion.
DenisovanThe Denisovans or Denisova hominins (prondɪˈniːsəvə ) are an extinct species or subspecies of archaic human that ranged across Asia during the Lower and Middle Paleolithic. Denisovans are known from few physical remains; consequently, most of what is known about them comes from DNA evidence. No formal species name has been established pending more complete fossil material. The first identification of a Denisovan individual occurred in 2010, based on mitochondrial DNA (mtDNA) extracted from a juvenile female finger bone excavated from the Siberian Denisova Cave in the Altai Mountains in 2008.
Anolis carolinensisAnolis carolinensis or green anole (USəˈnoʊ.li) (among other names below) is a tree-dwelling species of anole lizard native to the southeastern United States and introduced to islands in the Pacific and Caribbean. A small to medium-sized lizard, the green anole is a trunk-crown ecomorph and can change its color to several shades from brown to green. Other names include the Carolina anole, Carolina green anole, American anole, American green anole, North American green anole and red-throated anole.