Tuberculosis managementTuberculosis management describes the techniques and procedures utilized for treating tuberculosis (TB). The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months. During this initial period, Isoniazid is taken alongside pyridoxal phosphate to obviate peripheral neuropathy. Isoniazid is then taken coincident with rifampicin for the remaining four months of treatment.
Exploratory data analysisIn statistics, exploratory data analysis (EDA) is an approach of analyzing data sets to summarize their main characteristics, often using statistical graphics and other data visualization methods. A statistical model can be used or not, but primarily EDA is for seeing what the data can tell us beyond the formal modeling and thereby contrasts traditional hypothesis testing. Exploratory data analysis has been promoted by John Tukey since 1970 to encourage statisticians to explore the data, and possibly formulate hypotheses that could lead to new data collection and experiments.
Mycolic acidMycolic acids are long fatty acids found in the cell walls of the Mycolata taxon, a group of bacteria that includes Mycobacterium tuberculosis, the causative agent of the disease tuberculosis. They form the major component of the cell wall of mycolata species. Despite their name, mycolic acids have no biological link to fungi; the name arises from the filamentous appearance their presence gives mycolata under high magnification. The presence of mycolic acids in the cell wall also gives mycolata a distinct gross morphological trait known as "cording".
GlycocalyxThe glycocalyx (: glycocalyces or glycocalyxes), also known as the pericellular matrix and sometime cell coat, is a glycoprotein and glycolipid covering that surrounds the cell membranes of bacteria, epithelial cells, and other cells. It was described in a review article in 1970. Animal epithelial cells have a fuzz-like coating on the external surface of their plasma membranes. This viscous coating is the glycocalyx that consists of several carbohydrate moieties of membrane glycolipids and glycoproteins, which serve as backbone molecules for support.
Mapping cone (topology)In mathematics, especially homotopy theory, the mapping cone is a construction of topology, analogous to a quotient space. It is also called the homotopy cofiber, and also notated . Its dual, a fibration, is called the mapping fibre. The mapping cone can be understood to be a mapping cylinder , with one end of the cylinder collapsed to a point. Thus, mapping cones are frequently applied in the homotopy theory of pointed spaces. Given a map , the mapping cone is defined to be the quotient space of the mapping cylinder with respect to the equivalence relation , .
Mapping cylinderIn mathematics, specifically algebraic topology, the mapping cylinder of a continuous function between topological spaces and is the quotient where the denotes the disjoint union, and ∼ is the equivalence relation generated by That is, the mapping cylinder is obtained by gluing one end of to via the map . Notice that the "top" of the cylinder is homeomorphic to , while the "bottom" is the space . It is common to write for , and to use the notation or for the mapping cylinder construction.
