Signal transduction networks: topology, response and biochemical processes
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The mitogen-activated protein kinase (MAPK) cascades are ubiquitous in eukaryotic signal transduction, and these pathways are conserved in cells from yeast to mammals. They relay extracellular stimuli from the plasma membrane to targets in the cytoplasm an ...
A statistical physics perspective of complex networks: from the architecture of the Internet and the brain to the spreading of an epidemic Statistical physics has revealed itself as the ideal framework to describe large networks appearing in a variety of d ...
This paper describes a new kind of genetic representation called analog genetic encoding (AGE). The representation is aimed at the evolutionary synthesis and reverse engineering of circuits and networks such as analog electronic circuits, neural networks, ...
The mitogen activated protein kinase (MAPK) cascade is one of the most prominent and well-studied signaling networks. The pathway has control over such diverse cellular functions as cell proliferation, migration, and differentiation. In addn. to its well-d ...
In mammalian embryos, molecular cross-talk with extraembryonic tissues is essential to elaborate the primary body axes. Here, we review a series of reciprocal interactions that occur shortly after implantation in the uterus, and discuss how they are integr ...
The Drosophila peptidoglycan recognition protein SA (PGRP-SA) is critically involved in sensing bacterial infection and activating the Toll signaling pathway, which induces the expression of specific antimicrobial peptide genes. We have determined the crys ...
The mouse mammary gland is a complex tissue that proliferates and differentiates under the control of systemic hormones during puberty, pregnancy and lactation. Once a highly branched milk duct system has been established, during mid/late pregnancy, alveol ...
Distributed adaptive algorithms are proposed based on incremental and diffusion strategies. Adaptation rules that are suitable for ring topologies and general topologies are described. Both distributed LMS and RLS implementations are considered in order to ...
Light absorption by the visual pigment rhodopsin leads to vision via a complex signal transduction pathway that is initiated by the ultrafast and highly efficient photoreaction of its chromophore, the retinal protonated Schiff base (RPSB). Here, we investi ...
In this paper, we present an efficient measurement technique for the analysis of power line communication (PLC) signals. The frequency spectrum associated with PLC signals extends from 1 MHz to 30 MHz. The proposed technique can be applied to a network con ...