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Ultra-low-power design has been a challenging area for design of the sensor front-ends especially in the area of Wireless Body Sensor Nodes (WBSN), where a limited amount of power budget and hardware resources are available. Since introduction of Compressed Sensing, there has been a challenge to design CS-based low-power readout devices for different applications and among all for biomedical signals. Till now, different proposed realizations of the digital CS prove the suitability of using CS as an efficient low-power compression technique for compressible biomedical signals. However, these works mainly take advantages of only one aspect of the benefits of the CS. In this type of works, CS is usually used as a very low cost and easy to implement compression technique. This means that we should acquire the signal with traditional limitations on the bandwidth (BW) and later compresses it. However, the main power of the CS, which lies on the efficient data acquisition, remains untouched. Building on our previous work [1], where the suitability of the CS is proven for the compression of the ECG signals, and our investigation on ultra-low-power CS-based A2I devices [2] , here in this paper we propose a fully redesigned complete CS-based “Analog-to-information” (A/I) front-end for ECG signals. Our results show that proposed hybrid design easily outperforms the traditional implementation of CS with more than 11 times fold reduction in power consumption compared to standard implementation of CS. Moreover our design shows a very promising performance specially in high compression ratio.