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Protrusion-retraction switches and traction forces in spontaneous cell polarization

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Early Dynamometers (from Muscle to Steam Power)

Jean-François Loude

Spring balances, based on Hooke’s law, have been used for weighing since the early 18th century. At the end of the century, naturalists such as Buffon felt the need to quantify the muscular force of men (humans) and animals. The first practical, portable “ ...

2014

Each bacterial species has a characteristic shape, but the benefits of specific morphologies remain largely unknown. To understand potential functions for cell shape, we focused on the curved bacterium Caulobacter crescentus. Paradoxically, C. crescentus c ...

2014

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In the analysis of squeeze film haptic tactile feedback actuators, attention is focused on establishing an empirical model of the force generated on the user's finger. The model is based on finite-element simulations which take into account the real motion ...

Institute of Electrical and Electronics Engineers2014

Cell migration is a fundamental process in all animal cells. The ability of cell to migrate is crucial for many pathological and physiological conditions such as morphogenesis, the immune response to inflammatory or vascular diseases and cancer metastasis. ...

EPFL2013

Targeting and Modulating Tumor-Associated Sites with Novel Nanoparticle-Based Immunotherapies

Laura Jeanbart

Cancer is a global disease and a leading cause of death worldwide. While surgery, radiotherapy and chemotherapy comprise the classical tools to eradicate tumors, they do not cure cancer, cannot prevent metastases, lead to side effects, and most importantly ...

EPFL2013

The contribution of the host stress response to the pathogenesis of Pseudomonas entomophila in the Drosophila intestine

Sveta Chakrabarti

Recently, several studies done in Drosophila have revealed that efficient and rapid recovery from bacterial infection in the gut is possible only when bacterial clearance by the immune system is coordinated with repair through renewal of the epithelium dam ...

EPFL2013

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The cascaded transmission line theory of Paul and McKnight is used in this paper to predict near-end crosstalk (NEXT) and far-end crosstalk (FEXT) in a bundle of twisted wire pairs. The approach is validated using the CST Cable Studio commercial software a ...

Ieee-Inst Electrical Electronics Engineers Inc2013

Laboratory experiments which consist of releasing dry rigid non-cohesive grains or small bricks on an unconfined chute have been designed to investigate rock avalanche propagation mechanisms and to identify parameters influencing their deposit characterist ...

Springer Verlag2013

Ability to migrate is a fundamental property of all animal cells. Cell migration underlies such important physiological and pathological processes as embryonic development, immune response, tissue regeneration and cancer metastasis. As cell migration invol ...

EPFL2011

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Engineered artificial microenvironments hold enormous potential as models to study developmental, physiological, pathological, and regenerative processes under highly defined conditions. Such platforms aim at bridging the gap between traditional in vitro 2 ...

2011