Aging brainAging of the brain is a process of transformation of the brain in older age, including changes all individuals experience and those of illness (including unrecognised illness). Usually this refers to humans. Since life extension is only pertinent if accompanied by health span extension, and, more importantly, by preserving brain health and cognition, finding rejuvenating approaches that act simultaneously in peripheral tissues and in brain function is a key strategy for development of rejuvenating technology.
Big lieA big lie (große Lüge) is a gross distortion or misrepresentation of the truth primarily used as a political propaganda technique. The German expression was first used by Adolf Hitler in his book Mein Kampf (1925) to describe how people could be induced to believe so colossal a lie because they would not believe that someone "could have the impudence to distort the truth so infamously". Hitler claimed that the technique had been used by Jews to blame Germany's loss in World War I on German general Erich Ludendorff, who was a prominent nationalist political leader in the Weimar Republic.
Polynomial sequenceIn mathematics, a polynomial sequence is a sequence of polynomials indexed by the nonnegative integers 0, 1, 2, 3, ..., in which each index is equal to the degree of the corresponding polynomial. Polynomial sequences are a topic of interest in enumerative combinatorics and algebraic combinatorics, as well as applied mathematics. Some polynomial sequences arise in physics and approximation theory as the solutions of certain ordinary differential equations: Laguerre polynomials Chebyshev polynomials Legendre
Sheffer sequenceIn mathematics, a Sheffer sequence or poweroid is a polynomial sequence, i.e., a sequence (pn(x) : n = 0, 1, 2, 3, ...) of polynomials in which the index of each polynomial equals its degree, satisfying conditions related to the umbral calculus in combinatorics. They are named for Isador M. Sheffer. Fix a polynomial sequence (pn). Define a linear operator Q on polynomials in x by This determines Q on all polynomials. The polynomial sequence pn is a Sheffer sequence if the linear operator Q just defined is shift-equivariant; such a Q is then a delta operator.
Falling and rising factorialsIn mathematics, the falling factorial (sometimes called the descending factorial, falling sequential product, or lower factorial) is defined as the polynomial The rising factorial (sometimes called the Pochhammer function, Pochhammer polynomial, ascending factorial, rising sequential product, or upper factorial) is defined as The value of each is taken to be 1 (an empty product) when These symbols are collectively called factorial powers. The Pochhammer symbol, introduced by Leo August Pochhammer, is the notation (x)_n , where n is a non-negative integer.
AnimatorAn animator is an artist who creates multiple images, known as frames, which give an illusion of movement called animation when displayed in rapid sequence. Animators can work in a variety of fields including film, television, and video games. Animation is closely related to filmmaking and like filmmaking is extremely labor-intensive, which means that most significant works require the collaboration of several animators. The methods of creating the images or frames for an animation piece depend on the animators' artistic styles and their field.
Framing (social sciences)In the social sciences, framing comprises a set of concepts and theoretical perspectives on how individuals, groups, and societies organize, perceive, and communicate about reality. Framing can manifest in thought or interpersonal communication. Frames in thought consist of the mental representations, interpretations, and simplifications of reality. Frames in communication consist of the communication of frames between different actors. Framing is a key component of sociology, the study of social interaction among humans.